Hexane extract from black soldier fly prepupae: A novel immunomodulatory strategy against infection in zebrafish.

Background And Aim: infections in fish result in significant financial losses within aquaculture. Previous research indicates black soldier fly (BSF) prepupae provide immunomodulatory benefits through their fatty acids, chitin, and proteins. The study evaluated the impact of hexane extract from black soldier fly prepupae (HEBP) on interleukin (IL)-4 and IL-10 cytokine expression in zebrafish, both infected and uninfected with .

The immunomodulatory activity of against atopic dermatitis: Evidence-based on network pharmacology and molecular simulations.

Objectives: To explore the potential activity of (OA) against atopic dermatitis (AD).

Methods: Phytocompounds from OA were identified through chromatography analysis, then continued to target identification and functional annotation to explore the potential target of OA. Then, network pharmacology from annotated proteins determined protein targets for OA phytocompounds.

Association between diabetes mellitus, hypertension, and knee osteoarthritis in secondary referral hospitals in Indonesia with retrospective cross-sectional study.

Introduction: Osteoarthritis is a disease with degenerative joints. There are some risk factors for osteoarthritis, including age, gender, diabetes mellitus, smoking, and hypertension. The preview study also showed a relationship between osteoarthritis and diabetes mellitus.

Correlation between severity of knee osteoarthritis with gender of patients in Secondary Referral Hospital in Indonesia.

Aim Knee osteoarthritis is a common osteoarthritis, which limits individual's activity and affects aspects of daily life and quality of life. The prevalence of osteoarthritis in Indonesians is still high, reaching 12.7% in women and 15.

Characteristics of Grade 2 Disability in Indonesian Children with Leprosy: A Five-Year Multicenter Retrospective Study.

Background: One of the indicators of achieved leprosy control is lower new cases of leprosy with grade 2 disability (G2D), while zero new pediatric case with G2D is one of the targets of The Global Leprosy Strategy. This study aimed to describe the characteristics of leprosy in children with G2D from seven provincial hospitals in Indonesia, spanning a period of five years.

Methods: This was a descriptive and retrospective study with cross-sectional design.

Disseminated Herpes Zoster on a Child with Systemic Lupus Erythematosus and Lupus Nephritis.

Introduction: Disseminated herpes zoster (DHZ) is a complication of herpes zoster (HZ) associated with an immunocompromised state. Immunocompromised conditions in systemic lupus erythematosus (SLE) and lupus nephritis increase the incidence of DHZ.

Case: A 14-year-old girl was consulted with a complaint of painful reddish blisters for the previous 4 days.

Evaluation of nerve growth factor serum level for early detection of leprosy disability.

Introduction: this research aimed to analyze nerve growth factor (NGF) contents as diagnostic tools for early disability in leprosy patients and the cut-off point value.

Methods: research samples consisted of 79 leprosy patients with disability grade 0 or 1 who met the clinically approved inclusion criteria. The age of patients ranged from 14 to 50 years.

The Correlation of Semmes-Weinstein Monofilament Test with the Level of P-75 Neurotrophin as Marker of Nerve Damage in Leprosy.

Introduction: Leprosy is a chronic infectious disease caused by that causes damage to the peripheral nerve, particularly Schwann cells. Treatment is useful only to kill bacteria but not to recover peripheral nerve damage. However, early detection of peripheral nerve damage is necessary.