adhesion protein orchestrates caveolae-mediated apical junctional remodeling of epithelial barrier for translocation.

Unlabelled: The cellular junctional architecture remodeling by adhesion protein-heat shock protein 60 (LAP-Hsp60) interaction for () passage through the epithelial barrier is incompletely understood. Here, using the gerbil model, permissive to internalin (Inl) A/B-mediated pathways like in humans, we demonstrate that crosses the intestinal villi at 48 h post-infection. In contrast, the single isogenic ( or Δ) or double (Δ) mutant strains show significant defects.

Combined Effects of Clarifying Agents Improve Physicochemical, Microbial and Sensorial Qualities of Fresh Indian Gooseberry ( L.) Juice during Refrigerated Storage.

Using clarifying agents is essential in the production of fruit juice. This study utilized gelatin and bentonite as clarifying agents to improve the quality and shelf-life of Indian gooseberry juice (IGBJ). Different treatments were prepared using varying levels of gelatin and bentonite alone or in combination (1.

Multi-accelerant approach for rapid shelf-life determination of beverages in polymeric packaging.

An effective analysis method with multiple accelerant factors is needed for shelf-life determination and prediction for food products with reduced analysis time. Raising the storage temperature is the most common approach utilized in the conventional accelerated shelf-life test (ASLT) to reduce the shelf-life testing time of food. Oxygen pressure as an accelerant for the shelf-life determination of food products has not been given much attention even though it has shown a negative impact on food shelf-life.

Non-destructive processing of silver containing glass ceramic antibacterial coating on polymeric surgical mesh surfaces.

Surgical meshes composed of bioinert polymers such as polypropylene are widely used in millions of hernia repair procedures to prevent the recurrence of organ protrusion from the damaged abdominal wall. However, post-operative mesh infection remains a significant complication, elevating hernia recurrence risks from 3.6% to 10%, depending on the procedure type.

Secondary Cutaneous Mucormycosis Post-COVID-19: Case Series from a Tertiary Center.

Background: Mucormycosis is an angioinvasive mucorales fungal infection. Cutaneous type formed 10.5% of cases in India in precovid-19 era.

Optimal Design of Complementary Experiments for Parameter Estimation at Elevated Temperature of Food Processing.

Simultaneous estimation of thermal properties can be challenging, especially when the parameters are temperature-dependent. Previous research has shown that by using a complementary experiment, temperature-dependent thermal conductivity can be estimated using a single experiment. The objective of this study was to optimize the complementary experiments that can facilitate the simultaneous estimation of temperature-dependent thermal conductivity and volumetric heat capacity.

Polyethylene Terephthalate (PET) Bottle-to-Bottle Recycling for the Beverage Industry: A Review.

Disposal of plastic waste has become a widely discussed issue, due to the potential environmental impact of improper waste disposal. Polyethylene terephthalate (PET) packaging accounted for 44.7% of single-serve beverage packaging in the US in 2021, and 12% of global solid waste.

Dynamic Thermal Properties Estimation Using Sensitivity Coefficients for Rapid Heating Process.

Thermal conductivity determination of food at temperatures > 100 °C still remains a challenge. The objective of this study was to determine the temperature-dependent thermal conductivity of food using rapid heating (TPCell). The experiments were designed based on scaled sensitivity coefficient (SSC), and the estimated thermal conductivity of potato puree was compared between the constant temperature heating at 121.

Real-Time Detection of Fouling-Layer with a Non-Intrusive Continuous Sensor (NICS) during Thermal Processing in Food Manufacturing.

The fouling of indirect shell and coil heat exchanger by heavy whipping cream (HWC) and non-fat dry milk (NFDM) was studied at aseptic Ultra-High Temperature (UHT) processing conditions (140 °C) using a novel non-intrusive sensor. The sensor emitted a heat pulse intermittently throughout the duration of the process causing an incremental increase in temperature at the tube external surface. The temperature response of the sensor varied due to the radial growth of the fouling layer formed by certain components of the products.

Comparison of efficacy and safety of topical 1% nadifloxacin and tretinoin 0.025% combination therapy with 1% clindamycin and tretinoin 0.025% combination therapy in patients of mild-to-moderate acne.

Background: Topical retinoids in combination with antimicrobials have been proven to reduce acne lesions faster and to a greater degree than antimicrobial therapy alone .

Aims And Objectives: To compare the efficacy and safety of topical combination of 1% Nadifloxacin [NAD] and 0.025% Tretinoin [Tr] with 1% Clindamycin [CLN] and 0.

Migration of antioxidants from polylactic acid films: A parameter estimation approach and an overview of the current mass transfer models.

Migration studies of chemicals from contact materials have been widely conducted due to their importance in determining the safety and shelf life of a food product in their packages. The US Food and Drug Administration (FDA) and the European Food Safety Authority (EFSA) require this safety assessment for food contact materials. So, migration experiments are theoretically designed and experimentally conducted to obtain data that can be used to assess the kinetics of chemical release.

A case report of reactive solitary eccrine syringofibroadenoma.

Eccrine syringofibroadenoma is a very rare benign tumour of acrosyringium of eccrine sweat duct. Based on the evidences of known etiological factors, two forms have been proposed; reactive and nonreactive. Reactive forms are rarer, and on even rarer occasions, trauma complicated by secondary nonspecific infections may lead to the development of reactive eccrine syringofibroadenoma, as in our case.

Rapid Inverse Method to Measure Thermal Diffusivity of Low-Moisture Foods.

Thermal diffusivity is an important transport property needed in modeling and computations of transient heat transfer in basic food processing operations. In addition, the prediction of nutritional and microbial changes occurring in food during thermal processing requires knowledge of thermal diffusivity of foods. The objectives of this study were to develop a new nonisothermal and nonlinear determination method of thermal diffusivity and to measure the thermal diffusivity of low-moisture foods using that new method.

Generalized Morphea following Radiotherapy for an Intracranial Tumor.

Morphea is a localized scleroderma variety which can be circumscribed or generalized and is characterized by sclerotic plaques developing on trunk and limbs. Surgery and radiation have been implicated as etiological factors for the development of morphea. Majority of the radiation-induced morphea cases have occurred in patients with breast cancer.

Comparative Study of Efficacy and Safety of Topical Squaric Acid Dibutylester and Diphenylcyclopropenone for the Treatment of Alopecia Areata.

Background: Topical squaric acid dibutylester and diphenylcyclopropenone are still the most effective therapy for alopecia areata among widely available treatment options. Hence, it is important to know which one is more effective and safer between the two.

Aims: The aim of this study was to compare topical squaric acid dibutylester and diphenylcyclopropenone for the treatment of alopecia areata in terms of their efficacy and side effects.

Comparison of Efficacy, Safety and Cost-effectiveness of Rupatadine and Olopatadine in Patients of Chronic Spontaneous Urticaria: A Randomized, Double-blind, Comparative, Parallel Group Trial.

Objective: To compare efficacy, safety and cost-effectiveness of rupatadine and olopatadine in patients of chronic spontaneous urticaria.

Materials And Methods: A 6-week, single-centered, randomized, double blind, parallel group comparative clinical study was conducted on patients with chronic spontaneous urticaria. Following inclusion and exclusion criteria, 60 patients were recruited and were randomized to two treatment groups and received the respective drugs for 6 weeks.

Clinical effectiveness and safety of cetirizine versus rupatadine in chronic spontaneous urticaria: a randomized, double-blind, 6-week trial.

Background: Urticaria is a distressing condition associated with diverse clinical presentations. Chronic spontaneous urticaria (CsU) is characterized by wheals and angioedema. Its treatment requires an algorithmic approach to identify the optimum medication.

Evaluation of Cutaneous Drug Reactions in Patients Visiting Out Patient Departments of Indira Gandhi Government Medical College and Hospital (IGGMC and H), Nagpur.

Objectives: To detect cutaneous drug reactions through spontaneous reporting system in IGGMCand H, Nagpur and analyze them using standard assessment scales.

Materials And Methods: An observational, prospective study was performed in patients attending dermatology OPD of IGGMC and H, Nagpur from 1(st) June 05 to 31(st) May 09. Patients were examined for cutaneous drug reactions (CDRs) by spontaneous Adverse Drug Reaction reporting system.

Parameter estimation in food science.

Modeling includes two distinct parts, the forward problem and the inverse problem. The forward problem-computing y(t) given known parameters-has received much attention, especially with the explosion of commercial simulation software. What is rarely made clear is that the forward results can be no better than the accuracy of the parameters.