Publications by authors named "Dharmendra K Singh"

Background Magnetic resonance imaging (MRI) arthrography has been a mainstay in the diagnosis of musculoskeletal (MSK) joint-related pathology for decades. With the advent of MRI and further advancements incorporating powerful magnetic fields, the radiological landscape is undergoing a shift. The objective of this study is to evaluate the relevance and preference for MRI arthrography versus MRI among MSK radiologists in our current clinical practice across a range of geographic locations.

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The management of aggressive bone tumours requires a multidisciplinary approach, with radiologists playing a central role alongside clinicians and pathologists. Radiologists contribute significantly to diagnosing benign and some aggressive tumours, although complex cases often need histopathological confirmation. Their expertise in tumour characterization and extension assessment is crucial for treatment planning.

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Article Synopsis
  • The study investigates leukocytosis in children with diabetic ketoacidosis (DKA) compared to those with community-acquired pneumonia (CAP).
  • It analyzes various blood parameters, finding significant differences in the platelet-to-lymphocyte ratio (PLR) and platelet-to-monocyte ratio (PMR) between the two groups, although the neutrophil-to-lymphocyte ratio (NLR) showed no significant difference.
  • The results suggest that specific blood parameters could help predict clinical outcomes in children with DKA.
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  • Ultrasonography (USG) is used to diagnose and manage carpal tunnel syndrome (CTS), especially for patients with severe cases.
  • Surgical options for CTS include open or endoscopic release of the transverse carpal ligament, which can now be done more safely due to improved USG technology.
  • The text discusses a technical approach for performing a percutaneous thread carpal tunnel release using surgical-grade thread.
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Sensing and quantification of gas at low concentrations is of paramount importance, especially with highly flammable and explosive gases such as hydrogen. Standard gas sensing setups have a limit of measuring ultra-low concentrations of few parts per billion unless the external gas cylinders are changed to ones with low concentrations. In this work, we describe a home-built resistance based gas sensing setup that can sense across a wide concentration range, from parts per billion to parts per million, accurately.

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Enteric fever remains a significant public health problem in low- and middle-income countries with further challenges from emerging antimicrobial resistance. Our prospective study evaluated the current clinical and antimicrobial susceptibility profile of enteric fever in 88 children and compared it to previously established literature. Enteric fever usually presents with nonspecific signs and symptoms, with predominant respiratory complaints.

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Carpal tunnel syndrome (CTS), the most common entrapment neuropathy, is compression of the median nerve deep to transverse carpal ligament at wrist. Ultrasonography and electrophysiological study are complementary in the diagnosis and grading of CTS in appropriate clinical settings. The initial management of patients with CTS is conservative with medical therapy and splinting.

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  • The article discusses how Magnetic Resonance Imaging (MRI) is used to analyze traumatic brachial plexopathy (TBP) by locating injured nerve segments and assessing the severity of the damage.
  • It connects MRI findings of TBP with Sunderland's grading system for nerve injuries, which helps in developing treatment plans.
  • The review introduces a new five-part approach for understanding the radiological anatomy of the brachial plexus and outlines the necessary MRI protocols and key imaging signs related to TBP.
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Ewing's sarcoma is an aggressive primary malignant bone tumor that affects long and flat bones and is commonly seen in children and adolescents. The involvement of the foot especially the talus is an extremely rare entity with less than 15 cases reported in the literature. The rarity and atypical symptoms often lead to delays in diagnosis affecting the prognosis and survival.

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Objectives: To assess the advantage of the addition of shear wave elastography (SWE) to gray-scale sonography in the diagnosis of plantar fasciitis.

Methods: 30 subjects between 18-60 years of age with unilateral heel pain who were clinically suspected of having plantar fasciitis were included in this study. Their affected feet were taken as cases; while their contralateral feet served as controls.

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Evolution and functional necessities have compelled the great toe of the foot and its embryological kin, thumb, to have some tendoligamentous differences with a similar basic anatomical structure. This provides biomechanical advantage to these joints: the thumb is apposable and more mobile, ensuring hand dexterity and tool-handling, whereas the great toe is less mobile and more stable, ensuring weight bearing, strength, and stability for bipedal locomotion. This pictorial review will methodically illustrate the similarities and dissimilarities of the joint morphology and its tendoligamentous attachments at the level of carpometacarpal joint, metacarpophalangeal joint, and interphalangeal joints of thumb compared with tarsometatarsal joint, metatarsophalangeal joint, and interphalangeal joints of great toe.

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 Convulsive status epilepticus (CSE) is a common neurological emergency with high mortality, morbidity, and poor quality of life. There is a paucity of follow-up studies from developing nations in pediatric age group.  This article looks for clinico-etiological profile of CSE and estimates the immediate and short-term mortality in children with CSE and its predictive factors.

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Targeted cannulation of the nidus and subsequent thermal ablation is the basis of CT-guided radiofrequency ablation (RFA) of osteoid osteoma, which is considered nowadays as the treatment of choice. The majority of complications during this procedure are due to thermal injury of adjacent structures. Specific measures as per the anatomical location of osteoid osteoma can avoid the majority of complications.

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Sorghum [Sorghum bicolor (L.) Moench.] is a versatile crop, grown in 30 countries and a food source for nearly 500 million people globally.

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Background: Conventional glass ionomer cement (CGIC) has many beneficial properties, but it has poor physical and mechanical properties. Therefore, new glass ionomer cement (GIC) is manufactured by adding zinc to improve the mechanical properties of GIC ChemFil Rock. This material possesses better flexural tensile strength and compressive strength in comparison to conventional to CGIC.

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Background: Squamous cell carcinoma is the most frequent head-and-neck malignancy and chiefly encompasses malignancies of the upper aerodigestive tract, including the oral cavity, nasal cavity, paranasal sinuses, nasopharynx, oropharynx, hypopharynx, pharynx, and larynx.

Objectives: The current study was conducted to evaluate the incidence, prevalence, and correlation of oral and esophageal cancer in the Indian population.

Materials And Methods: The present study was conducted on the basis of data collected from various government cancer hospitals in India.

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Background: Mechanical plaque removal is considered the gold standard for controlling and prevention of plaque and gingivitis. The present study was conducted to evaluate the efficacy of commercially available herbal dentifrices in comparison with conventional dentifrices against two of the common oral microbes, namely and .

Materials And Methods: To determine the antimicrobial properties of individual dentifrices, the zone of inhibition on the blood agar plates was measured and also disc diffusion method was used for testing the antibacterial properties for which a thin paper disc containing the antimicrobial agent was applied on a culture of bacteria grown on agar media.

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Background: We aimed to compare the rate of diagnostically successful vertebral biopsies using conventional bone biopsy needles versus those performed with bone biopsy needles with an acquisition cradle.

Methods: We retrospectively analyzed the data of patients who underwent CT-guided vertebral biopsy between December 2017 to December 2019 at our institute. From December 2017 to November 2018, the procedure was performed on 185 patients using an 11G conventional bone biopsy needle, Jamshidi needleTM "(group 1)".

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Background: Dengue and malaria co-infection has been reported in several case reports. We aim to study effect of malaria co-infection on clinical outcomes of dengue infection.

Methods: Records of 623 children with dengue infection, based on NS-1 antigen and IgM ELISA testing, were collected.

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Vigilin (Vgl1) is essential for heterochromatin formation, chromosome segregation, and mRNA stability and is associated with autism spectrum disorders and cancer: vigilin, for example, can suppress proto-oncogene c- expression in breast cancer. Conserved from yeast to humans, vigilin is an RNA-binding protein with 14 tandemly arranged nonidentical hnRNP K-type homology (KH) domains. Here, we report that vigilin depletion increased cell sensitivity to cisplatin- or ionizing radiation (IR)-induced cell death and genomic instability due to defective DNA repair.

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Airborne transmission is one of the routes for the spread of COVID-19 which is caused by inhalation of smaller droplets containing SARS-CoV-2 (i.e., either virus-laden particulate matter: PM and/or droplet nuclei) in an indoor environment.

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Objective: Thyroid functions in preterm newborns may be altered in the first week of life. Hypothyroxinemia has been commonly reported in these babies, which could be due to the immaturity of the hypothalamic pituitary thyroid axis or acute illness. It could have a long-term impact on the developing brain of these babies.

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Synovial plicae are normal remnants of synovial membranes within the knee joint cavity and are usually asymptomatic. Pathological infrapatellar plica, which is mostly due to plica injury, may be a potential cause of anterior knee pain, but is often overlooked and under-reported on magnetic resonance imaging (MRI). This pictorial review illustrates the MRI findings of infrapatellar plica injury and associated knee injuries, with emphasis on its differentiation from the mimics of plica injury.

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