Publications by authors named "Dharmendra K"

Article Synopsis
  • Antimicrobial resistance (AMR) is a critical global health issue that renders conventional antimicrobial agents ineffective, necessitating new treatments and global cooperation to address it.
  • The study highlights the potential of plant metabolites (like terpenes and alkaloids) for their antibacterial and antifungal properties, which target microbial functions and can work alongside traditional antibiotics.
  • The review underscores the need for ongoing research into pharmacological therapies and the therapeutic promise of plant-derived compounds in combating AMR.
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Uterine fibroids (UFs) are a common benign gynecological tumor that affect the majority of women over their lifetime. Several pharmacological agents are available to reduce the size of fibroids and ameliorate the symptoms of UF. However, these drugs are expensive and are usually associated with profound side effects.

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Colonic targeting has gained increasing interest over the past years, not just for the transport of drugs for the treatment of local diseases associated with the colon but also for its potential for transporting peptides and proteins, particularly low molecular weight peptide drugs. Without protection, such peptide drugs are usually digested within the gastric and small intestinal sections. In the present work Layer-By-Layer (LBL) self-assembly was utilized to make Aceclofenac single bilayer microcapsules produced by sequential adsorption of positively charged chitosan and negatively charged Pectin on the external surface of negatively charged Aceclofenac microcrystals.

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