Comparative Effectiveness Research: The Impact of Biologic Agents in Ethnic Minorities With Metastatic Colorectal Cancer.

Background: Biologic agents have improved the outcomes of patients with metastatic colorectal cancer (mCRC). However, the clinical trials included a predominately white population (85%), with Hispanic and black patients underrepresented. Thus, the real world benefit for the latter remains unknown.

Sleep-isolated Trichotillomania (SITTM): A Case Report.

We report a case of sleep-isolated trichotillomania admitted to the hospital for alcohol detoxification. It would be helpful for patients with sleep-isolated trichotillomania to have diagnostic polysomnography to identify any other sleep-related pathology and correlate sleep-isolated trichotillomania behaviors with the sleep cycle to identify specific treatment for sleep-isolated trichotillomania.

Antipsychotic drugs and safety concerns for breast-feeding infants.

Antipsychotic drugs prescribed to treat psychiatric symptoms during the postpartum period are secreted into breast milk. Because breast-feeding is crucial to infant development, it is important to select a medication that poses the fewest adverse consequences. Aripiprazole, haloperidol, perphenazine, and trifluoperazine demonstrate no known developmental dangers.

Would You Recognize Fahr's Disease if You Saw It?

Idiopathic basal ganglia calcification or Fahr's disease is a neurological condition with a prominent movement disorder. Diagnostically, brain imaging with computerized tomographic scanning reveals bilateral brain calcifications, usually of the basal ganglia. A positive family history is very common, along with a generational anticipatory effect, thus familial basal ganglia calcification is an alternative name.