Publications by authors named "Dharmaraj Saravanan"

Article Synopsis
  • Candida albicans is becoming resistant to current antifungal medications, prompting the need for new natural treatment options.
  • The leaf extract of Cassia spectabilis was tested and found to be nontoxic, with significant effects on C. albicans, including potassium leakage and changes in cell wall proteins.
  • Treated C. albicans cells exhibited morphological damage and abnormalities, indicating that C. spectabilis extract is a promising potential antifungal agent.
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Plants play important roles in human life not only as suppliers of oxygen but also as a fundamental resource to sustain the human race on this earthly plane. Plants also play a major role in our nutrition by converting energy from the sun during photosynthesis. In addition, plants have been used extensively in traditional medicine since time immemorial.

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The genus Cassia, comprising about 600 species widely distributed worldwide is well known for its diverse biological and pharmacological properties. Cassia spectabilis (sin Senna spectabilis) (DC) Irwin et Barn (Fabaceae) is widely grown as an ornamental plant in tropical and subtropical areas. C.

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Aim: To evaluate the usefulness of differentially expressed proteins from colorectal cancer (CRC) tissues for differentiating cancer and normal tissues.

Methods: A Proteomic approach was used to identify the differentially expressed proteins between CRC and normal tissues. The proteins were extracted using Tris buffer and thiourea lysis buffer (TLB) for extraction of aqueous soluble and membrane-associated proteins, respectively.

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Breast cancer is a leading cause of mortality in women. In Malaysia, it is the most common cancer to affect women. The most common form of breast cancer is infiltrating ductal carcinoma (IDC).

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Background: The objective of this study was to investigate the antioxidant and hepatoprotective effects of methanolic extracts of L. edodes and the determination of their total phenolics content.

Results: The amount of total phenolics was estimated to be 70.

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