Publications by authors named "Dharav Naik"
Article Synopsis
- A variety of quinoline compounds have been shown to have pharmaceutical effects, particularly against HIV-1, with specific derivatives like 2-styrylquinolines and 8-hydroxyquinolines inhibiting the HIV-1 integrase enzyme.
- Researchers synthesized thirty-one new quinoline derivatives, testing them for their effectiveness against HIV-1, and found that Compound 31 demonstrated the highest antiviral activity in cell assays.
- Further tests indicated that Compound 31 is effective in inhibiting both virus entry and cell fusion, showing strong potential as an anti-HIV-1 treatment compared to existing inhibitors.
