Publications by authors named "Dhanya M"
Article Synopsis
- Oral lichen planus (OLP) is a chronic inflammatory condition affecting the oral mucosa, which can severely impact patients' quality of life due to discomfort and anxiety.
- A study at Saveetha Dental College analyzed the anxiety and depression levels of 212 OLP patients, with their data collected over one year, including factors like age, gender, and associated medical conditions.
- The study found that the most affected age group was 51-60 years, predominantly female, with many reporting burning sensations as the main symptom, and a small percentage having comorbidities like Grinspan syndrome.
Article Synopsis
- Oral potentially malignant disorders (OPMD) are abnormal tissue changes that may lead to oral cancer, making it important to identify high-risk lesions and measure oxidative stress markers like lipid peroxidase (LPO).
- A study analyzed LPO levels across four groups: oral cancer patients, healthy controls, and two types of OPMD (oral leukoplakia and others), finding significantly higher LPO levels in the oral cancer group (171.86 nmol/L) compared to others.
- The results suggest that increased LPO levels are associated with greater oxidative stress in oral cancer, indicating that LPO could serve as a valuable marker for assessing tissue damage in individuals with OPMDs.
Background: Photodynamic therapy can be used to treat a variety of lesions noninvasively, including oral cancer. High-power laser therapy has also been used to treat oral squamous cell carcinomas. The two main components of photodynamic treatment are the photosensitizer and the light source.
View Article and Find Full Text PDFBackground: Photodynamic therapy is one of the non-invasive treatment modalities used to treat a wide range of oral mucosal lesions including oral leukoplakia, oral lichen planus, post-radiation-induced oral mucositis, and aphthous ulcerations. High-level laser therapy has also been employed in the management of oral squamous cell carcinomas (OSCCs). Photodynamic therapy includes three major components: photosensitizer, light source, and presence of oxygen.
View Article and Find Full Text PDFIntroduction Osteoporosis is a disease that is characterised by low bone mineral density (BMD), and loss of structural and biomechanical properties that are essential in maintaining bone homeostasis. Osteoporosis is diagnosed by clinical measurement of BMD and is the best predictor of osteoporosis. The study was conducted with the aim of assessing the effectiveness of orthopantomogram (OPG) as a screening tool for osteoporosis in postmenopausal women and chronic drug users.
View Article and Find Full Text PDFOral squamous cell carcinomas (OSCCs) fall between the sixth and eighth most common cancers. The prevention of cancer and the treatment of the disease depends on early diagnosis. To encourage dental professionals to use light-based detection techniques in clinical practice, this systematic review aims to evaluate the literature on the effectiveness of chemiluminescence and autofluorescent imaging equipment in the detection of OSCC and OPMDs.
View Article and Find Full Text PDFMyristica fragrans (Houtt.) is an evergreen tree native to the Maluku Islands, Indonesia. M.
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- Symptoms of phytoplasma infection were noted in cauliflower (cultivar NS60N) in Kerala, India, with disease incidence reaching up to 10%, characterized by stunted growth, floral malformations, and stem flattening.
- Testing for the presence of phytoplasma used nested PCR on symptomatic and asymptomatic plants, yielding consistent amplification of specific genes only in symptomatic samples, with subsequent cloning and sequencing confirming a 99.77% match to a reference strain.
- Phylogenetic analysis indicated that the phytoplasma linked to the observed cauliflower disease belonged to the 16SrXIV-A subgroup, with no signs of infection found in asymptomatic plants.
The essential oil (EO) from leaf, mace, kernel, and seed of Houtt. growing in the Western Ghats, India was investigated for the first time. The EO was extracted by hydrodistillation and analysed by GC-MS.
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- Small cardamom (Elettaria cardamomum) is traditionally used for various health issues like asthma, infections, and digestive disorders, highlighting its significance in both traditional and modern medicine.
- The study aims to evaluate traditional uses of cardamom and compare them with contemporary research, focusing on its chemical properties and health benefits.
- Findings reveal that cardamom contains essential nutrients and compounds, providing numerous health benefits such as antioxidant and antibacterial effects, and it is commonly used in cooking and fragrances.
The objective of this study was to examine the bioactive flavonoids and carotenoids concentration in fifteen south Indian spice and two tree nut species using high performance liquid chromatography (HPLC). Among four flavonoids, catechin concentration was the highest in all spices and nuts and ranged between 97.1 and 1745.
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- Indian cardamom, primarily grown in southern India at altitudes between 900 and 1400 meters, has been analyzed for its essential oil composition using gas chromatography-mass spectrometry (GC-MS).
- The study found significant levels of the major monoterpene 1, 8-Cineole, with concentrations between 28.94% and 34.91% in various cardamom varieties, along with other important monoterpenes.
- Additionally, the research identified sesquiterpenes and ester constituents, highlighting α-Terpinyl acetate as the most prominent ester in one variety, marking the first detailed report on the phytochemical profiles of recent Indian cardamom varieties.
Salivary glucose as a diagnostic tool in Type II diabetes mellitus: A case-control study.
Niger J Clin Pract
January 2018
Background And Objectives: The prevalence of diabetes mellitus is increasing steadily in India. Understanding blood glucose level is the key to both diagnosis and management of diabetes mellitus. However, there is an on-going need for improvements in noninvasive, point-of-care tools for the diagnosis and prognosis of diabetes.
View Article and Find Full Text PDFBackground: This study assessed the correlation between nicotine dependence and salivary cotinine levels in tobacco chewers and checked the reliability of Fagerstorm test in tobacco cessation programmes.
Methods: The study sample included 75 tobacco chewers aged between 20 to 50 years. Self-reported nicotine dependence was evaluated using Fagerstorm Test for Nicotine dependence-smokeless tobacco questionnaire.
Adaptation and validation of the Malayalam pediatric voice handicap index.
Int J Pediatr Otorhinolaryngol
September 2015
Objectives: The aim of the present study was to adapt and validate the English version of pediatric voice handicap index (pVHI) into Malayalam language.
Methods: The English version of pediatric voice handicap index was translated into Malayalam language using parallel back translation. The translated version was content validated by three qualified speech language pathologists.
Exophytic growth of the oral cavity often presents a diagnostic challenge because a diverse group of the pathologic process can produce such lesions. Inflammatory hyperplasia is one of the important etiology behind the exophytic growths of the oral cavity. The pyogenic granuloma (PG) is the most common type of inflammatory hyperplasia found in the oral cavity especially in the gingiva.
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