A non-autochthonous human rabies case in the historically rabies-free Andaman And Nicobar Islands, India.

Rabies, a fatal zoonotic viral disease claims numerous lives annually worldwide, particularly in Asia and Africa. Despite the high prevalence of rabies in India, the Andaman and Nicobar Islands have historically maintained a rabies-free status. This report documents the first non-indigenous case of human rabies in these islands, emphasizing the imperative for heightened surveillance measures.

Amelioration: An Innovative Approach to Behavior Management Based on Cognitive Process.

Aim: The study aimed to determine the applicability of psychological traits identified by Piaget sixty years ago to children in the current generation and to utilize these traits clinically for behavior modification.

Methods: A cross-sectional study was conducted with 200 participants aged 4-7, divided into four groups. Three tests were administered to evaluate the manifestation of preoperational features.

Buffalopox: An emerging zoonotic challenge.

As a variant of Vaccinia virus, Buffalopox virus is known to cause Buffalopox disease. In recent times, sporadic outbreaks of the infection in humans have been reported, especially in the endemic countries of Southeast Asia. Though mortality has not been high, associated morbidity is significant.

Tracing the journey of poxviruses: insights from history.

The historical significance of the poxviruses is profound, largely due to the enduring impact left by smallpox virus across many centuries. The elimination of smallpox is a remarkable accomplishment in the history of science and medicine, with centuries of devoted efforts resulting in the development and widespread administration of smallpox vaccines. This review provides insight into the pivotal historical events involving medically significant poxviruses.

Effectiveness of Aculief acupressure device on pain perception during local anesthesia in children: A double-blinded study.

Aim: The aim of this study was to evaluate the effect of the Aculief acupressure device on the reduction of pain during local anesthesia (LA) in children and to compare it with the cryotherapy technique.

Methodology: 20 children of age group between 6 and 9 years, requiring pulpectomy or extraction bilaterally were chosen for the study. After ethical clearance and parental consent, children who were not experienced to prior local anesthesia were chosen for the study.

Evaluation of Microleakage of Stainless Steel Crowns and Pedo Jacket Crowns after Cementation With Different Luting Cements.

Aim: The present research was conducted to assess the microleakage of stainless steel crowns along with pedo jacket crowns following cementation with different luting cements.

Materials And Methods: A total of 60 deciduous teeth subjected to extraction were employed in this research. These 60 specimens were randomly divided into two groups: Group I: Stainless steel crowns and Group II: Pedo Jacket crowns.

A Comparison of NovaMin and Casein Phosphopeptide-Amorphous Calcium Phosphate Fluoride on Enamel Remineralization - An Study Using Scanning Electron Microscope and DIAGNOdent.

Aim: The aim of this study was to compare the efficacy of NovaMin (SHY-NM) and casein phosphopeptide-amorphous calcium phosphate fluoride (CPP-ACPF) (tooth mousse plus) on enamel remineralization using DIAGNOdent and scanning electron microscope (SEM).

Methodology: Eighty-six natural permanent maxillary first premolars were selected and randomly divided into two groups of 43 each, Group A (NovaMin) and Group B (CPP-ACPF). All the samples were assessed using DIAGNOdent (KaVo) at the baseline, after demineralization, and remineralization after 7 days.

Parosteal Osteosarcoma of the Proximal Phalanx of a Finger.

Osteogenic sarcoma of the hand is very rare and fewer than 50 cases have been reported. There are only 2 previously reported cases of parosteal osteosarcoma involving the phalanges. We report a primary parosteal osteosarcoma involving the proximal phalanx of the right middle finger in a 20-year-old woman, which was managed by ray amputation.

Diabetes induces fibrotic changes in the lung through the activation of TGF-β signaling pathways.

In the long term, diabetes profoundly affects multiple organs, such as the kidney, heart, brain, liver, and eyes. The gradual loss of function in these vital organs contributes to mortality. Nonetheless, the effects of diabetes on the lung tissue are not well understood.

Oncogenic Actions of SKP2 Involves Deregulation of CDK1 Turnover Mediated by FOXM1.

Cyclin-dependent kinases (cdks) are central catalytic units of cell division cycle. Among the cdk family members, cdk1 has critical roles in multiple phases of the cell cycle. Aberrant expression or hyper-actions of cdk1 are tumorigenic and yet the complex oncogenic network that regulates its turnover is poorly understood.

Diagnosis of leiomyosarcoma of colon.

Leiomyosarcomas of colon are rare tumors accounting for less than 1% of cases which are often misdiagnosed and confused with gastrointestinal stromal tumor (GIST). We report a case of 54-year-old male presenting with abdominal pain with computer tomography (CT) showing a retroperitoneal mass. He underwent laparotomy and surgical excision of mass was done.

RAPD, SCAR and conserved 18S rDNA markers for a red-listed and endemic medicinal plant species, Knema andamanica (Myristicaceae).

Knema andamanica is a red-listed endemic medicinal species of Myristicaceae restricted to Andaman and Nicobar (A&N) Islands, India. This species is used in tribal medicines and has immense bioprospective potential. With a view to generate suitable genomic markers for classification and identification, we have generated RAPD, SCAR and conserved 18S rDNA markers from K.

Multiparticulate system for colon targeted delivery of ondansetron.

Targeted delivery of drugs to colon has the potential for local treatment of a variety of colonic diseases. The main objective of the study was to develop a multiparticulate system containing chitosan microspheres for the colon targeted delivery of ondansetron for the treatment of irritable bowel syndrome. This work combines pH-dependent solubility of eudragit S-100 polymers and microbial degradability of chitosan polymers.

Development, characterization and cross species amplification of polymorphic microsatellite markers from expressed sequence tags of turmeric (Curcuma longa L.).

Expressed sequence tags (ESTs) from turmeric (Curcuma longa L.) were used for the screening of type and frequency of Class I (hypervariable) simple sequence repeats (SSRs). A total of 231 microsatellite repeats were detected from 12,593 EST sequences of turmeric after redundancy elimination.

Isolation and amplification of genomic DNA from recalcitrant dried berries of black pepper (Piper nigrum L.)--a medicinal spice.

Black pepper is an important medicinal spice traded internationally. The extraction of high quality genomic DNA for PCR amplification from dried black pepper is challenging because of the presence of the exceptionally large amount of oxidized polyphenolic compounds, polysaccharides and other secondary metabolites. Here we report a modified hexadecyl trimethyl ammonium bromide (CTAB) protocol by incorporating potassium acetate and a final PEG precipitation step to isolate PCR amplifiable genomic DNA from dried and powdered berries of black pepper.