Tuning the Reactivity of Copper(II)-Nitrite Core Towards Nitric Oxide Generation.

Insights into the molecular mechanism and factors affecting nitrite-to-NO transformation at transition metal sites are essential for developing sustainable technologies relevant to NO-based therapeutics, waste water treatment, and agriculture. A set of copper(II)-nitrite complexes 1-4 have been isolated employing tridentate pincer-type ligands (L, L, L, L) featuring systematically varied donors. Although the X-ray crystal structures of the copper(II)-nitrite cores in 1-4 are comparable, electrochemical studies on complexes 1-4 reveal that redox properties of these complexes differ due to the changes in the σ-donor abilities of the phenolate/N-heterocycle based donor sites.

Cross-Talks Between Sulfane Sulfur and Thiol at a Zinc(II) Site.

Transformations of sulfane sulfur compounds (e. g. organic polysulfides (R-S -R, n>2) and elemental sulfur (S )) play pivotal roles in the biochemical landscape of sulfur, and thus supports signaling activities of H S.