Publications by authors named "Dhanushya Nagarajan"
Article Synopsis
- The high rates of breast cancer in post-menopausal women are linked to active estrogen metabolism and receptor protein expression, with letrozole being a key treatment option.
- Letrozole functions as an aromatase inhibitor, used for treating hormone receptor-positive breast cancer and also showing promise in promoting fertility in pre-menopausal women.
- The review covers letrozole's effects on the body, including its pharmacokinetics, adverse effects on various organs, and its role in inducing cancer cell death while affecting follicle development and estrogen production.
Lung Emphysema is an abnormal enlargement of the air sacs followed by the destruction of alveolar walls without any prominent fibrosis. This study primarily identifies the differentially expressed genes (DEGs), interactions between them, and their significant involvement in the activated signaling cascades. The dataset with ID GSE1122 (five normal lung tissue samples, five of usual emphysema, and five of alpha-1 antitrypsin deficiency-related emphysema) from the gene expression omnibus (GEO) was analyzed using the GEO2R tool.
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