MicroRNA-34a-3p and its target tumor necrosis factor-α in the regulation of South Indian oral squamous cell carcinoma population.

Background: The most frequent head and neck cancer is oral squamous cell carcinoma (OSCC), the common histological cancer of the oral cavity and is one of the most prevalent forms of cancer globally. It has been known that there are several biomarkers and therapeutic targets that have been discovered for OSCC, but none of them were effective against the progression of OSCC. Interestingly, small non-coding RNAs termed microRNAs (miRNAs) regulate cellular activity by targeting numerous signaling pathways or genes that either promote or repress the progression of diseases.

Estimation of L-carnitine levels in diabetic completely edentulous patients for implant diagnosis: A cross-sectional study.

Background: Carnitine is effective in preventing the accumulation of end products related to lipid peroxidation due to its anti-inflammatory and antioxidant effects. Carnitine also exerts a significant anti-inflammatory role through the downregulation of the nuclear factor kappa beta pathway, which leads to a decrease in the expression of pro-inflammatory cytokines.The aim of the study was to estimate the L-carnitine (L-C) levels in diabetic completely edentulous patients.

Knowledge, Attitude, and Perception Regarding the Financial Aspects of Prosthetic Rehabilitation Using Dental Implants: A Double-Questionnaire-Based Study.

To assess up to date patient and doctor perceived costs of dental implant surgery among the Indian population as there is a lack of information regarding patients' awareness of dental implants. Two online questionnaire forms were sent over the internet to the Indian population and the Indian dentists and dental students regarding the knowledge, attitude and perception regarding the dental implant surgery for rehabilitation of a single missing tooth. Statistical analysis was then carried out using SPSS software version 23.

Characterization and antimicrobial activity of cerium oxide nanoparticles synthesized using neem and ginger.

The aim of this study is to analyze and characterize the antimicrobial effect of cerium oxide nanoparticles (NP) synthesized using neem and ginger. Finely grounded neem and ginger powder were taken and mixed with distilled water. This mixture was then heated and filtered.

Comparative analysis of weld strength of nickel-chromium and cobalt-chromium base metal alloys when submitted to tungsten inert gas welding.

Long span base metal alloy fixed prosthesis and partial dental prosthesis frameworks most often require welding for better fit and adaptation. The type of metal alloys used and its effect on the weld strength of the prosthesis have to be investigated. The aim of the study is to comparatively analyze the weld strength of nickel-chromium (Ni-Cr) and cobalt-chromium (Co-Cr) base metal alloys when subjected to tungsten inert gas (TIG) welding.

Evaluation of accuracy and time taken to make an open tray implant impressions with two techniques.

Implant dentistry's emergence and acceptance have provided physicians with a wide range of new options for fixed and removable rehabilitation. The eventual replacement of the lost tooth is the ultimate success, and this can be accomplished using recognized prosthodontic methods. The present study aims to evaluate the time and dimensional accuracy of implant definitive models with an open tray impression with two different techniques.

Phosphorescent wax - The novel approach of innovation.

The present invention relates to dental compositions that include a phosphorescent material, more particularly, adding phosphorescent material to waxes that used in dentistry. The aim of the study is to develop a wax that has innate phosphorescent properties. Three groups of samples were taken in which the phosphorescent material was added.

Awareness on resonance frequency analysis in dental implantology among dental practitioners and dental students.

In a partial or entirely independent jaw, oral implantology is a technique in dentistry used to enhance the function of mastication, esthetics, and phonation. An important diagnostic aspect for the effectiveness of implant therapy is the stability of the implants. This study aims to measure dental professionals' and dental students' knowledge of resonance frequency analysis (RFA) in dental implantology.

Comparative analysis of pink and white esthetics of anterior full veneer crown: Indian scenario.

A goal of modern dentistry is to make an esthetic outcome as one of the major modalities in dental treatment. In recent years, more emphasis has been given to esthetic parameters, especially in the anterior regions. The aim of this study was to evaluate the presence of change in pink and white esthetics scores after giving crowns in a single tooth.

Awareness on D-dimer assay among dental students.

D-dimer molecules are formed by the degradation of cross-linked fibrin during the process of fibrinolysis. The formation of D-dimer requires the activity of activated factor XIII (factor XIIIa), plasmin, and thrombin. To assess the awareness about D-dimer assay among dental students.

Knowledge and awareness on neurolept anesthesia among dental students.

N20 omission or addition to the combination of an opioid and neuroleptic is referred to as neuroleptanalgesia and neuroleptanesthesia, respectively. Conscious sedation is the result of this evolution. The requirement for high-quality anesthesia that is also related with speedier recovery, improved comfort, and lower costs all support the concept of neuroleptanesthesia.

Mini-Implants in Dentistry - A Review.

Mini-implants were introduced as an alternative to standard implants for use in narrow alveolar ridges due to their smaller length and size. They are also used to provide anchorage in orthodontic treatments. Mini-implants offer simplified treatment procedures with a flat learning curve, low cost, and a possible flapless surgical procedure that can decrease post-surgical morbidity.

Deciphering the Role of MicroRNAs in Neuroblastoma.

Neuroblastoma (NB) is a type of peripheral sympathetic nervous system cancer that most commonly affects children. It is caused by the improper differentiation of primitive neural crest cells during embryonic development. Although NB occurs for 8% of paediatric cancers, it accounts for 15% of cancer-related deaths.

Comparative analysis of different impression techniques in relation to single tooth impression.

It is of interest to compare the accuracy of three different impression techniques for a single tooth impression. We used 3 groups with 15 samples each in this study. Group 1: Putty and light body in a sectional stock tray; Group 2: Monophase and extra light body in a sectional stock tray; Group 3: Matrix impression technique.

Rehabilitation of squamous cell carcinoma defect with two-piece hollow bulb obturator prosthesis - A case report.

Two-piece hollow bulb obturator maxillofacial prosthesis for hemi-maxillectomy defect is given after surgical resection due to oral squamous cell carcinoma. Maxillofacial prosthodontists play a pivotal role in construction of prosthesis. Unique choices are made in prosthesis design depending on the clinical representation.

Assessment of intraoral scanning technology for multiple implant impressions - A systematic review and meta-analysis.

Background: Intraoral scanner (IOS) is a medical device used for capturing direct optical impressions and composed of a handheld camera (hardware), a computer and software. Digital impressions by intraoral scanning have become an increasingly popular alternative to conventional impressions. The aim of this systematic review is to assess the studies regarding the various available technologies for IOS and evaluate the most accurate IOS system for cases with multiple implants and identify the factors that can influence its accuracy.

Cervical and Incisal Marginal Discrepancy in Ceramic Laminate Veneering Materials: A SEM Analysis.

Context: Marginal discrepancy influenced by the choice of processing material used for the ceramic laminate veneers needs to be explored further for better clinical application.

Aims: This study aimed to evaluate the amount of cervical and incisal marginal discrepancy associated with different ceramic laminate veneering materials.

Settings And Design: This was an experimental, single-blinded, trial.

Evaluation of the influence of blood glucose level on oral candidal colonization in complete denture wearers with Type-II Diabetes Mellitus: An in vivo Study.

Background: Candidal colonization in complete denture wearers is a commonly encountered condition that worsens in the presence of untreated Diabetes Mellitus. The aim of this study was to evaluate the correlation between oral candidiasis in denture-bearing mucosa and elevated blood glucose levels in complete denture wearers and to evaluate the effect of oral hypoglycemic drug therapy in controlling oral candidal colonization in denture-bearing mucosa of complete denture wearers with Type II Diabetes Mellitus.

Materials And Methods: This prospective observational study involved the participation of 15 complete denture wearers with Type II Diabetes Mellitus.

Comparative evaluation of tensile bond strength of a polyvinyl acetate-based resilient liner following various denture base surface pre-treatment methods and immersion in artificial salivary medium: An in vitro study.

Background And Aim: This study was formulated to evaluate and estimate the influence of various denture base resin surface pre-treatments (chemical and mechanical and combinations) upon tensile bond strength between a poly vinyl acetate-based denture liner and a denture base resin.

Materials And Methods: A universal testing machine was used for determining the bond strength of the liner to surface pre-treated acrylic resin blocks. The data was analyzed by one-way analysis of variance and the t-test (α =.