Exosome Isolation from Pericardial Fluids.

Extracellular vehicles such as exosomes which lie in the size range of 30-150 nm have gained significant attention due to their ability to contain molecular cargoes. These vesicles are released by various cells and are found to stably carry their molecular cargoes to recipient cells via different biological fluids. Therefore, exosomes isolated from various fluids such as plasma, urine, and pericardial fluid have been extensively studied in recent years.

Upregulation of microRNA-532 enhances cardiomyocyte apoptosis in the diabetic heart.

Type 2 diabetes has a strong association with the development of cardiovascular disease, which is grouped as diabetic heart disease (DHD). DHD is associated with the progressive loss of cardiovascular cells through the alteration of molecular signalling pathways associated with cell death. In this study, we sought to determine whether diabetes induces dysregulation of miR-532 and if this is associated with accentuated apoptosis.