Photodynamic and antibacterial studies of template-assisted FeO-TiO nanocomposites.

FeO-TiO (FT) nanocomposites were successfully synthesized by template-assisted precipitation reaction using Polyvinylpyrrolidone-Polyethylene glycol (PVP-PEG), Tween-80 (T-80) and Cetyltrimethylammomium bromide (CTAB) as templates. The prepared nanocomposites were characterized by XRD, SEM, EDX, UV-DRS, FT-IR, and FT-Raman spectroscopic analysis. The photohemolysis studies were done in human erythrocytes and the cell viability studies were done in HeLa cell lines under the irradiation of an LED light source.

Enhanced photocatalytic and photodynamic activity of chitosan and garlic loaded CdO-TiO hybrid bionanomaterials.

Herein, the work addresses the synthesis of biomaterials (chitosan and garlic) loaded CdO-TiO hybrid nanocomposites for photocatalytic water treatment and photodynamic cancer therapeutic applications that were reported the first time. CdO-TiO (CT) nanocomposites were synthesized and loaded with the biomaterials such as chitosan and garlic by simple sol-gel method. The nanomaterials were characterized and the photodegradation of three model pollutants, Methylene blue (MB), Methyl orange (MO) and Rhodamine B (Rh-B) was opted to investigate the efficiency of the synthesized photocatalyst under the solar light.

MnO nanoparticles bearing 5-amino-2-mercapto benzimidazole moiety as antibacterial and antifungal agents.

The antibacterial and antifungal effects of non-functionalized and surface-functionalized MnO nanoparticles were comparatively analyzed to reason out the potential changes in antimicrobial activities due to functionalization with 5-amino-2-mercapto benzimidazole (AMB) molecule. The surface functionalization of MnO nanoparticles with AMB molecule was confirmed by the XRD result, which shows the shift in 2 values with noticeable peaks. The surface morphology and functionalization of MnO nanoparticles were additionally confirmed by HR-SEM and EDAX studies.

Biomaterial (Garlic and Chitosan)-Doped WO-TiO Hybrid Nanocomposites: Their Solar Light Photocatalytic and Antibacterial Activities.

In this work, WO-TiO, chitosan-blended WO-TiO, and garlic-loaded WO-TiO nanocomposites were synthesized by the sol-gel and precipitation technique. The synthesized nanocomposites were characterized by XRD, FE-SEM, HR-TEM, EDX, UV-DRS, FT-IR, and TG-DTA analysis. The photocatalytic efficiency of the three synthesized nanocomposites on the degradation of dyes such as rhodamine B (Rh-B), methylene blue (MB), and methyl orange (MO) as organic pollutants was evaluated under solar light irradiation.

Photodynamic cancer therapy: role of Ag- and Au-based hybrid nano-photosensitizers.

The utilization of photodynamic therapy (PDT) has been rapidly increasing due to its advantage as an effective treatment modality for cancer. The organic photosensitizers employed for PDT have some disadvantages, including high toxicity, non-selectivity toward tumors and poor absorption of light. The low light penetration into the tumor sites resulting from low wavelength of absorption and long-term skin photosensitivity.

Preparation and characterization of core-shell type Ag@SiO nanoparticles for photodynamic cancer therapy.

With recent scientific developments, Photodynamic therapy (PDT) offers the promisie to become incorporated into the mainstream of cancer therapy. Noble metal based nano-PDT is increasing due to its advantages in the field of biomedicine. In this study, noble metal based Ag@SiO core-shell nanoparticles were synthesized and to confirm the core-shell structure they were characterized by UV-vis, XRD, FTIR, TEM, and EDX.

Photodynamic activity and DNA binding studies of Pd@SiO core-shell nanoparticles in vitro.

Metal-semiconductor core-shell type Pd@SiO nanoparticles (NPs) were successfully synthesized by Stober's method and the product was characterized by UV-vis, XRD, FT-IR, SEM, HR-TEM and EDX techniques. In vitro Photodynamic activity and DNA binding studies of Pd@SiO core shell nanoparticles were studied. Cell viability of the core-shell nanoparticles against HeLa cell line was screened by MTT assay after exposing at different light doses.

Study of photodynamic activity of Au@SiO2 core-shell nanoparticles in vitro.

Metal-semiconductor core-shell type Au@SiO2 nanoparticles were prepared by Stober's method. They were characterized by absorption, XRD, HR-TEM and EDAX techniques. The resulting modified core-shell nanoparticles shows that the formation of singlet oxygen, which was confirmed by ESR technique.

DNA intercalation studies and antimicrobial activity of Ag@ZrO2 core-shell nanoparticles in vitro.

Ag@ZrO2 core-shell nanoparticles were prepared by one pot simultaneous reduction of AgNO3 and hydrolysis of zirconium (IV) isopropoxide. The formation of core-shell nanoparticles was confirmed by absorption, XRD, and HR-TEM techniques. The antibacterial activity of Ag@ZrO2 core-shell nanoparticles against Escherichia coli and Staphylococcus aureus and the antifungal properties against Candida albicans, Candida glabrata, Aspergillus niger and Aspergillus flavus were examined by the agar diffusion method.

Comparison of antibacterial activities of Ag@TiO2 and Ag@SiO2 core-shell nanoparticles.

Core-shell type Ag@TiO2 nanoparticles were prepared by one pot simultaneous reduction of AgNO3 and hydrolysis of Ti (IV) isopropoxide and Ag@SiO2 core-shell nanoparticles were prepared by Stober's method. They were characterized by absorption, XRD, and HR-TEM techniques. XRD patterns show the presence of anatase form of TiO2 and amorphous form of SiO2 and the noble metal (Ag).