Cognitive bias in depression may increase sensitivity to judgmental appraisal of communicative cues. Nonverbal communication encompassing co-speech gestures is crucial for social functioning and is perceived differentially by men and women, however, little is known about the effect of depression on the perception of appraisal. We investigate if a cognitive bias influences the perception of appraisal and judgement of nonverbal communication in major depressive disorder (MDD).
View Article and Find Full Text PDFThe article "Central serotonin modulates neural responses to virtual violent actions in emotion regulation networks", written by Dhana Wolf, Martin Klasen, Patrick Eisner, Florian D. Zepf, Mikhail Zvyagintsev, Nicola Palomero‑Gallagher, René Weber, Albrecht Eisert, Klaus Mathiak was originally published electronically on the publisher's internet portal (currently SpringerLink) on June, 08, 2018 without open access.
View Article and Find Full Text PDFAggressive behavior is associated with dysfunctional frontolimbic emotion regulation circuits. Recent findings suggest serotonin as a primary transmitter for prefrontal amygdala control. However, the association between serotonin levels, amygdala regulation, and aggression is still a matter of debate.
View Article and Find Full Text PDFSocial interactions arise from patterns of communicative signs, whose perception and interpretation require a multitude of cognitive functions. The semiotic framework of Peirce's Universal Categories (UCs) laid ground for a novel cognitive-semiotic typology of social interactions. During functional magnetic resonance imaging (fMRI), 16 volunteers watched a movie narrative encompassing verbal and non-verbal social interactions.
View Article and Find Full Text PDFDisruptions in the cortico-limbic emotion regulation networks have been linked to depression, anxiety, impulsivity, and aggression. Altered transmission of the central nervous serotonin (5-HT) contributes to dysfunctions in the cognitive control of emotions. To date, studies relating to pharmaco-fMRI challenging of the 5-HT system have focused on emotion processing for facial expressions.
View Article and Find Full Text PDFFace-to-face communication is multimodal; it encompasses spoken words, facial expressions, gaze, and co-speech gestures. In contrast to linguistic symbols (e.g.
View Article and Find Full Text PDFBrain Struct Funct
March 2018
Low expressing alleles of the MAOA gene (MAOA-L) have been associated with an increased risk for developing an aggressive personality. This suggests an MAOA-L-specific neurobiological vulnerability associated with trait aggression. The neural networks underlying this vulnerability are unknown.
View Article and Find Full Text PDFIntroduction: A gene-environment interaction between expression genotypes of the monoamine oxidase A (MAOA) and adverse childhood experience increases the risk of antisocial behavior. However, the neural underpinnings of this interaction remain uninvestigated. A cortico-limbic circuit involving the prefrontal cortex (PFC) and the amygdala is central to the suppression of aggressive impulses and is modulated by serotonin (5-HT).
View Article and Find Full Text PDFSalient exogenous stimuli modulate attentional processes and lead to attention shifts-even across modalities and at a pre-attentive level. Stimulus properties such as hemispheric laterality and emotional valence influence processing, but their specific interaction in audio-visual attention paradigms remains ambiguous. We conducted an fMRI experiment to investigate the interaction of supramodal spatial congruency, emotional salience, and stimulus presentation side on neural processes of attention modulation.
View Article and Find Full Text PDFCombined EEG-fMRI analysis correlates time courses from single electrodes or independent EEG components with the hemodynamic response. Implementing information from only one electrode, however, may miss relevant information from complex electrophysiological networks. Component based analysis, in turn, depends on a priori knowledge of the signal topography.
View Article and Find Full Text PDFThe production of chemokines by astrocytes constitutes an important component of neuroinflammatory processes in the brain. As the transcriptional activator retinoic acid (RA), used for chemotherapy and dermatological applications, exerts anti-inflammatory effects on monocytes and lymphocytes, we have tested whether the physiologically occurring isomer, all-trans RA, affects chemokine expression by astrocytes. Under control conditions, primary cultures of murine cortical astrocytes expressed no or very low levels of CCL and CXCL chemokines.
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