Publications by authors named "Dhan Keshar Khadka"

Article Synopsis
  • The study aimed to compare the effectiveness and safety of intralesional triamcinolone acetonide (TAC) alone versus a combination of TAC and 5-fluorouracil (5-FU) in treating keloids and hypertrophic scars over 12 weeks.
  • In a randomized trial involving 66 patients, both treatments showed reductions in scar parameters, but the combination therapy demonstrated significantly better results in terms of efficacy, faster response, and fewer complications.
  • The findings suggest that while both treatments are viable, the combination of TAC and 5-FU is more effective and safer than TAC alone; however, the study has limitations such as being conducted at a single center and lacking long-term follow-up.
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Background: Paediatric dermatoses vary vastly from adult dermatoses in terms of clinical presentation, management, and prognosis thereby generating special interest in this field. Many factors like geographical area, climatic exposure, seasons, culture, socioeconomic factors, hygiene, dietary habits, literacy influences pattern of skin diseases in children resulting in marked variation in prevalence and pattern.

Objectives: This study aims to find out association of socio-demographic factors and personal hygiene with infectious childhood dermatoses.

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Lymphangiectasia is dilatation of normal superficial lymphatic vessels due to damage or obstruction of deep lymphatic vessels leading to increased lymphatic pressure and engorgement of dermal lymphatics due to varying causes. Lymphangiectasia clinically presents as thick-walled, translucent vesicles and papules with chronic lymphedema rarely involving the scrotum. Here we report a patient with acquired lymphangiectasia of the scrotum secondary to surgery for hydrocele successfully treated with radiofrequency ablation.

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Sporotrichoid-lymphocutaneous-pattern is classically seen in sporotrichosis, though also present in other infections like atypical mycobacteriosis and leishmaniasis. Cutaneous atypical mycobacterial infection presents as localized lesions in immunocompetent and is widespread in immunosuppressed patients. Here, we present a case of sporotrichoid-lymphocutaneous infection due to atypical mycobacteria, in a fish-seller under immunosuppressants.

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Introduction: Periungual, palmar, and plantar warts are difficult to treat with poor treatment response. Intralesional (IL) bleomycin has shown promising results for their treatment in a few reports. However, we need further evidence before opting it for treating difficult sites and resistant warts.

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