Restricted Intramolecular Rotation: A Dual Fluorescence Response to Hg Quenching and Ag Enhancement in Live Rhizoctonia Solani Cells.

A novel imidazo[1,2-a]pyridine derivative probe (R) was designed, synthesized, and characterized via various characterization techniques, such as ESI-MS, H NMR, C NMR, and Dept-135 NMR. The data obtained from single-crystal XRD reveal that probe R has a coplanar configuration and is part of the monoclinic crystal system, designated the P2(1)/n space group. The fluorescence of (R) is further enhanced by silver (I) ions.

Wavelength specific aggregation induced emission in aqueous media permits selective detection of Ag and Hg ions.

A new 1,8-naphthalimide derivative (probe 1) adopts V-shaped structure, emits fluorescence and displays the Mie effect and aggregation-induced emission (AIE). Selective interactions of thiophilic Ag and Hg ions (10 µM) with 1 (10 µM) resulted in AIEs at 499 and 521 nm, respectively. Both Ag and Hg induce the formation of 1:2 complexes with 1, leading to the formation of AIE active aggregates with an average size of 423 and 198 nm, respectively.

Green synthesis of zinc ferrite nanoparticles from Nyctanthes arbor-tristis: unveiling larvicidal potential, protein binding affinity and photocatalytic activities.

Environmental pollution, being a major concern worldwide, needs a unique and ecofriendly solution. To answer this, researchers are aiming in utilizing plant extracts for the synthesis of nanoparticles. These NPs synthesized using plant extracts provide a potential, environmentally benign technique for biological and photocatalytic applications.

A fluorescent chemosensor for selective detection of chromium (III) ions in environmentally and biologically relevant samples.

A simple single step one pot multicomponent reaction was performed to synthesize N-(tert-butyl)-2-(furan-2-yl)imidazo[1,2-a]pyridine-3-amine (TBFIPA). The synthesized TBFIPA was subjected to library of cations to study its ability for selective and sensitive detection of specific metal ions. Selective detection of chromium ions by TBFIPA were found from the significant hypsochromic shift (335 nm → 285 nm) in the UV-Visible spectra.

Anti-fungal effects of novel N-(tert-butyl)-2-(pyridin-2-yl)imidazo[1,2-a]pyridin-3-amine derivative and it's in-vitro, in-silico, and mode of action against Candida spp.

Imidazoles are a category of azole antifungals that encompass compounds such as ketoconazole, miconazole, esomeprazole, and clotrimazole. In contrast, the triazoles group, which includes fluconazole, voriconazole, and itraconazole, also plays a significant role. The rise of antibiotic resistance in fungal pathogens has evolved into a substantial global public health concern.

Coordination of Distal Carboxylate Anion Alters Metal Ion Specific Binding in Imidazo[1,2-a]pyridine Congeners.

Imidazo[1,2-a]pyridine derivatives have excellent potential for chelation with transition metal ions. Two new imidazo[1,2-a]pyridine-8-carboxylates were synthesized and characterized by H NMR, C NMR, HRMS, and single crystal-XRD techniques. Methyl carboxylate (probe 1) turns on fluorescence upon coordination with Zn, while sodium carboxylate (probe 2) turns off its fluorescence upon coordination with Co or Cu ions present in aqueous acetonitrile medium.