Publications by authors named "Dezong Li"
Chem Pharm Bull (Tokyo)
April 2017
Article Synopsis
- Postoperative pain is a complicated response that often peaks within 48 hours after surgery, commonly managed by local anesthetics like ropivacaine due to their effectiveness and low addiction risk.
- Researchers developed a temperature-sensitive gel made from PLGA-PEG-PLGA to prolong the analgesic effect of ropivacaine, which can switch from liquid to gel form slightly below body temperature.
- Inrat studies demonstrated that this gel significantly extended pain relief from a single injection to 48 hours, outperforming standard ropivacaine solutions.
