Enhancing the Stability and Anticancer Activity of Asparaginase Through Nanoparticle Immobilization: A Biotechnological Perspective on Nano Chitosan.

There is a shortage in the experimental research directly comparing the effectiveness of different nanoparticles in boosting asparaginase (ASNase) activity. This study assessed the impact of various nanoparticles on enhancing ASNase activity, stability, and anticancer effects through immobilization. ASNase was immobilized on different nanoparticles, and its efficiency was measured.

Versus Chitinase as an Anti-inflammatory and Antifungal Agent Against Human Pathogenic Fungi.

Fungal pathogens cause over a billion human infections annually, leading to more than 1.6 million deaths each year. The scarcity of available antifungal drugs intensifies the public health threat posed by human pathogenic fungal infections.

Phytochemical Composition and Bioactivities of Some Hydrophytes: Antioxidant, Antiparasitic, Antibacterial, and Anticancer Properties and Mechanisms.

Few researches have explored the production of pharmaceuticals from aquatic plants. Therefore, this study explored, for the first time, the phytochemical composition and bioactivities of ten aquatic plants. Aquatic plant shoots from various Nile River canals were collected, dried, and ground for aqueous extract preparation.

Antioxidant and Antibacterial Activities of Nano-probiotics Versus Free Probiotics Against Gastrointestinal Pathogenic Bacteria.

Unlabelled: Antibiotic-resistant pathogenic bacteria and the oxidative stress related to their infections are dangerous health problems. Finding new safe, effective antibacterial and antioxidant agents is an urgent global need. Probiotics are a strong candidate for possible antibacterial and antioxidant agents.

Agricultural wastes: a new promising source for phenylalanine ammonia-lyase as anticancer agent.

The present study aims to investigate the physicochemical characteristics of phenylalanine ammonia-lyase (PAL) extracted from agricultural waste and its potential use as an anticancer agent in comparison to microbial PAL. We extracted and partially purified PAL from agricultural waste sources. We assessed the temperature and pH range of PAL and determined enzyme kinetics parameters including Michaelis constants (Km), maximum velocity (Vmax), and specificity constant values (Vmax/Km).

Control the carcinogenic bacteria with new polysaccharides from agricultural wastes.

Agriculture activities industries produce a huge amount of waste every year. Agricultural wastes are a great source of natural polysaccharides characterized by accessibility, biocompatibility, and ease of modification. Finding new safe antibacterial agents has become one of the top priorities of health organizations worldwide.

Effect of yeast application on soil health and root metabolic status of corn seedlings under drought stress.

The soil enzymes are the heart of the biochemical reactions that occur in the soil saving the soil nutrients needed for plant growth. Recently yeast's importance as plant growth-promoting microorganisms has great attention. This study evaluated the effect of yeast application on the soil enzymes activity and root metabolic status in corn plants under drought stress.

Antibacterial Activity of Some Medicinal Plants in Al Baha Region, Saudi Arabia, Against Carcinogenic Bacteria Related to Gastrointestinal Cancers.

Background: Gastrointestinal cancers are the most dangerous cancers all over the world. The gut microbiota dysbiosis increases the risk of GI cancers and induces the host's susceptibility to carcinogenic bacteria. Antibiotic resistance is rising in these bacteria.

Plant asparaginase versus microbial asparaginase as anticancer agent.

The considerable effect of enzymes on human health draws great attention to enzyme-based drugs (therapeutic enzymes), in recent times. L-asparaginase (ASNase) is a well-known therapeutic enzyme. It has varied applications and is a single molecule for the treatment of multiple diseases.

Anticancer Activity of Aqueous Fenugreek Seed Extract Against Pancreatic Cancer, Histological Evidence.

Objectives: Pancreatic cancer is one of the malignant tumors in the digestive system all over the world. It has a very low survival rate. Although there is a great advancement in its therapy either through radiotherapy, chemotherapy, or other therapies, the overall survival is still less than 24 months.

Microbial Azurin Immobilized on Nano-Chitosan as Anticancer and Antibacterial Agent Against Gastrointestinal Cancers and Related Bacteria.

Objectives: To discover new natural effective anticancer agents and new antibacterial agents against antibiotic-resistant bacteria which are the most serious public health concern. Another important concern is drug delivery which is the transport of pharmaceutical compounds to have a therapeutic effect in organisms having a disease. Azurin is a promising anticancer agent produced from Pseudomonas aeruginosa.

Nano-peroxidase a Promising Anti-inflammatory and Antibacterial Agent Against Bacteria and Inflammation Related to Colorectal Cancer.

Background: Colorectal cancer (CRC) is one of the most common causes of cancer death in the world. Although genes are considered the most importantcauses that contribute to CRC, the intestinal microorganisms are an important player. Recently, various studies ensured the role of microbial infection and the ensuing inflammation in colon cancer initiation and progression.

Onion Extract Encapsulated on Nano Chitosan: a Promising Anticancer Agent.

Background: Onion (Allium cepa) is very rich in nutritional and pharmaceutical components, such as saponins, tannins, alkaloids, steroids, and phenols. Many recent researches approved its anticancer activity against various cancer cell lines. In this paper, we attempt to improve its anticancer activity with encapsulation on nano chitosan.