Association between different insulin resistance indices and all-cause mortality in patients with diabetic kidney disease: a prospective cohort study.

Aim: Previous research has shown a strong association between insulin resistance (IR) and both the onset and advancement of diabetic kidney disease (DKD). This research focuses on examining the relationship between IR and all-cause mortality in individuals with DKD.

Methods: This study utilized data obtained from the National Health and Nutrition Examination Survey (NHANES), spanning the years 2001 to 2018.

Specific Enrichment of Carrying Microorganisms with Nitrogen Fixation and Dissimilatory Nitrate Reduction Function Enhances Arsenic Methylation in Plant Rhizosphere Soil.

Plants can recruit microorganisms to enhance soil arsenic (As) removal and nitrogen (N) turnover, but how microbial As methylation in the rhizosphere is affected by N biotransformation is not well understood. Here, we used acetylene reduction assay, gene amplicon, and metagenome sequencing to evaluate the influence of N biotransformation on As methylation in the rhizosphere of , a potential As hyperaccumulator. was grown in mining soils (MS) and artificial As-contaminated soils (AS) over two generations in a controlled pot experiment.

Influence of enriched nitrate reducing bacteria communities on bacterial community structure and groundwater condition during in situ bioremediation of nitrate in acidic uranium-contaminated groundwater.

In-situ leaching (ISL) is the predominant technology used in uranium mining currently, although it leads to significant environmental challenges. Nitrates, a key component in leaching agents, not only pose a threat to human health but also impede the bioreduction of U(VI) in uranium-contaminated water. In this study, the nitrate reducing bacterial (NRB) communities adapted to acidic uranium-contaminated groundwater from a site in Northwest China were gained by an enrichment micro-model.

Organophosphorus mineralizing-Streptomyces species underpins uranate immobilization and phosphorus availability in uranium tailings.

Phosphate-solubilizing bacteria (PSB) are important but often overlooked regulators of uranium (U) cycling in soil. However, the impact of PSB on uranate fixation coupled with the decomposition of recalcitrant phosphorus (P) in mining land remains poorly understood. Here, we combined gene amplicon sequencing, metagenome and metatranscriptome sequencing analysis and strain isolation to explore the effects of PSB on the stabilization of uranate and P availability in U mining areas.

Phytic acid-functionalized polyamidoxime/alginate hydrogel for targeted uranium extraction from acidic wastewater.

Efficient removal of uranium from radioactive wastewater is crucial for both environmental protection and sustainable development of nuclear energy. However, selectively extracting uranium from acidic wastewater remains a significant challenge. Here we present a phytic acid-functionalized polyamidoxime/alginate hydrogel (PAG) via a facile one-step hydrothermal reaction.

LncRNA CTBP1-AS inhibits TP63-mediated activation of S100A14 during prostate cancer progression.

Long noncoding RNAs (lncRNAs) have emerged as important molecules and potential new targets for human cancers. This study investigates the function of lncRNA CTBP1 antisense RNA (CTBP1-AS) in prostate cancer (PCa) and explores the entailed molecular mechanism. Aberrantly expressed genes potentially correlated with PCa progression were probed using integrated bioinformatics analyses.

Synergistic effects of hydrogen peroxide and phosphate on uranium(VI) immobilization: implications for the remediation of groundwater at decommissioned in situ leaching uranium mine.

The processes of acid in situ leaching (ISL) uranium (U) mines cause the pollution of groundwater. Phosphate (PO) has the potential to immobilize U in groundwater through forming highly insoluble phosphate minerals, but the performance is highly restricted by low pH and high sulfate concentration. In this study, hydrogen peroxide (HO) and PO were synergistically used for immobilizing U based on the specific properties of groundwater from a decommissioned acid ISL U mine.

Preparation of core-shell composite materials capable of slowly releasing phosphate and their remediation performance of uranium-contaminated groundwater.

Acid in-situ leach uranium mining significantly alters the geochemistry of the ore zone, and leaves uranium, residual acid, as well as other potential contaminants in groundwater, which bring harm to human health and ecological environment. Many investigators have been trying to propose remediation strategies for the uranium-contaminated groundwater. Phosphate is an effective immobilization reagent of uranium in the groundwater.

Effects of low dose radiation on behavior rhythm of zebrafish (Danio rerio).

Biological rhythm refers to the internal regulation of various life activities of an organism, which are determined by the specific time structure sequences of each individual. Behavior rhythm is the most intuitive embodiment of biological rhythm. To study the effect of low dose radiation on behavioral rhythm, zebrafish (Danio rerio) was used as a model organism in this study.

Feasibility of uranium tailings for cemented backfill and its environmental effects.

Surface storage of uranium tailings presents a potential threat to the environment and human health. Cemented backfill can be used to dispose of tailings and control the ground pressure of stopes, providing a new approach for the in-situ seal of heap leaching uranium tailings (HLUTs). The backfilling characteristics of HLUTs were investigated by analyzing the release mechanism of sulfuric acid in HLUTs, the rheological properties of backfill slurry, as well as the strength development and microscopic characteristics of cemented HLUTs backfill (CUTB).

Effects of dissolved organic matter molecules on the sequestration and stability of uranium during the transformation of Fe (oxyhydr)oxides.

Amorphous ferrihydrite (Fh) is abundant in aquatic environments and sediments, and often coprecipitates with dissolved organic matter (DOM) to form mineral-organic aggregates. The Fe(II)-catalyzed transformation of Fh to crystalline Fe (oxyhydr)oxides (e.g.

Survival and risk factors among upper tract urothelial carcinoma patients after radical nephroureterectomy in Northeast China.

Objective: The study objective was to investigate the prognostic risk factors related to overall survival (OS), cancer-specific survival (CSS), recurrence-free survival (RFS), and metastasis-free survival (MFS) after radical nephroureterectomy (RNU) for upper tract urothelial carcinoma (UTUC). Patients were then divided into different risk groups (based on their number of prognostic risk factors), and specific postoperative treatment plans were formulated for patients in different risk groups.

Methods: We retrospectively analyzed the data of 401 patients with UTUC who underwent RNU between 2010 and 2020.

Unveiling the m6A Methylation Regulator Links between Prostate Cancer and Periodontitis by Transcriptomic Analysis.

Objective: To identify the N6-methyladenosine (m6A) methylation regulator genes linking prostate adenocarcinoma (PRAD) and periodontitis (PD).

Materials And Methods: PD and TCGA-PRAD GEO datasets were downloaded and analyzed through differential expression analysis to determine the differentially expressed genes (DEGs) deregulated in both conditions. Twenty-three m6A RNA methylation-related genes were downloaded in total.

Coupled variations of dissolved organic matter distribution and iron (oxyhydr)oxides transformation: Effects on the kinetics of uranium adsorption and desorption.

The interactions between dissolved organic matter (DOM) molecules and minerals play significant roles in affecting the fate of carbon and contaminants in soil environment. However, the mechanisms controlling the variations of DOM molecules distribution during the transformation of Fe (oxyhydr)oxides, and the effects of these variations on contaminant behaviors are still largely unknown. In this study, the dynamic variations of DOM properties and distributions, and the kinetics of uranium adsorption on and desorption from Fe (oxyhydr)oxides during the transformation were investigated, employing a combination of Orbitrap mass spectrometry (MS), high-resolution transmission electron microscopy (HR-TEM), and kinetic experiments.

Remediation of uranium-contaminated acidic red soil by rice husk biochar.

Uranium (U) in the U-contaminated acidic red soil exhibits high mobility. In the present study, rice husk was used to produce biochar to remediate U-contaminated red soil under acid precipitation. Firstly, batch adsorption experiments showed that the dissolution of alkaline substance in biochar could buffer the pH value of acidic solution.

Efficient removal of U(VI) in acidic environment with spent coffee grounds derived hydrogel.

In this study, humic-like substances (HLSs) was extracted from spent coffee grounds (SCGs), and it together with poly acrylic acid (PAA), was used for the first time to synthesize hydrogel material, namely HLSs/PAA gel, by one-step radical polymerization. Its maximum theoretical sorption capacity toward U(VI) at pH 3.00 was 661.

Identification of Ferroptosis Biomarker in AHH-1 Lymphocytes Associated with Low Dose Radiation.

The impact of long-term low-dose radiation on human health has always been a concern. Long-term low-dose gamma radiation causes cells continuous injury and causes chromosomal mutations to greatly increase the chance of cancer. Because it is significant to identify biomarkers for long-term low-dose gamma radiation, we investigate the influence of low dose rate on the gene expressions in the AHH-1 lymphocytes cell line (AHH-1 cells) for long-term irradiation.

iTRAQ-Based Proteomic Profiling of Potential Biomarkers in Rat Serum for Uranium Tailing Suspension Intratracheal Instillation.

Protection against low-dose ionizing radiation is of great significance. Uranium tailings are formed as a byproduct of uranium mining and a potential risk to organisms. In this study, we identified potential biomarkers associated with exposure to low-dose radiation from uranium tailings.

Effects of Low-Dose Gamma-Ray Radiation on Apoptosis and Development of Zebrafish Embryo Brain.

To investigate the effects of low-dose γ irradiation on apoptosis and development of the brain in zebrafish embryos, cumulative 15 mGy doses of γ rays from a 137Cs source were used to irradiate zebrafish embryos at 2 h post-fertilization (hpf) for 120 h. Apoptosis of the brain, brain morphological development, cell submicroscopic structure and mRNA expression were analyzed, respectively. Results indicate that after 15 mGy exposure, the apoptosis of zebrafish brain increased, vacuoles appeared in brain tissue, some organelles were damaged and vacuoles appeared locally in brain cells.

Photocatalytic reduction of U(VI) in wastewater by mGO/g-CN nanocomposite under visible LED light irradiation.

Efficient elimination of U(VI) from uranium wastewater is an urgent task for sustainable nuclear energy and environmental protection. In this study, magnetic graphene oxide decorated graphitic carbon nitride (mGO/g-CN) nanocomposite was prepared and used for photocatalytic reduction of U(VI) in wastewater under visible LED light irradiation for the first time. The batch experiments indicated that the mGO/g-CN (mGCN) nanocomposite could efficiently reduce U(VI) under visible LED light, and a high U(VI) extraction capacity of 2880.

Transport of uranium(VI) in red soil in South China: influence of initial pH and carbonate concentration.

Uranium-contaminated wastewater associated with uranium (U) mining and processing inevitably releases into soil environment. In order to assess the risk of U wastewater contamination to groundwater through percolation, U adsorption and transport behavior in a typical red soil in South China was investigated through batch adsorption and column experiments, and initial pH and carbonate concentration were considered of the high-sulfate background electrolyte solution. Results demonstrated that U adsorption isotherms followed the Freundlich model.

Enhanced phytoremediation of uranium contaminated soil by artificially constructed plant community plots.

In order to develop an artificially constructed plant community plot for the enhanced phytoremediation of uranium contaminated soils, three uranium accumulators including Bamboo-willow (Salix sp.), Paspalum scrobiculatum linn and Macleaya cordata were used to construct four artificial plant community plots, and greenhouse experiments were conducted to investigate the bioaccumulation of uranium by the plants and the organic acid content, enzyme activity, and the change of microbial community structure in their rhizosphere soils. The transfer factor (TF) and the total bioaccumulation amount (TBA) of uranium were used to describe remediation efficiencies in this paper.

Experimental study on radon exhalation behavior of heap leaching uranium ore column with dilute sulfuric acid.

In order to study the radon release behavior when heap leaching uranium ores with dilute sulfuric acid, unleached uranium ores from a uranium mine in southern China were selected as test samples. Adopting parameters from leaching processes commonly used in uranium mines, a laboratory experiment was carried out for 21 days with a one-dimensional acid heap leaching experimental column. The surface radon exhalation rate of uranium ore column was determined by static accumulation method while spraying with deionized water and dilute sulfuric acid.

4-Sulfonylcalix[6]Arene Modified Fe₃O₄@ Biosorbents for Effective Removal of Uranium(VI) from Aqueous Solutions.

A biosorbent, 4-sulfonylcalix[6]arene modified Fe₃O₄@ (MFSC), was successfully prepared through a two-step route for the effective removal of uranium (U(VI)) from aqueous solutions with high selectivity. The structure of MFSC was characterized by FT-IR, SEM, XRD, TGA and VSM, respectively. The impacts of various experimental parameters were investigated in detail.