Early activation of macrophage-2 with IL-4 in stromal vascular fraction increases VEGF levels and adipocyte count and maintains volume of fat graft in Wistar rats ().

Several previous studies have demonstrated the benefits of early macrophage 2 activation fat grafts supplemented with macrophage culture. However, this approach is considered impractical in clinical settings because of intraperitoneal induction use. The aim of this study was to investigate the effect of early stromal vascular fraction (SVF) macrophage-2 activation with IL-4 on fat graft survival compared to SVF alone using an animal model for better fat graft viability.

Pain management with virtual reality in burn patients: a literature review.

Burns are injuries to the skin or the underlying tissue system caused by heat, radiation, electricity, friction or chemicals. Burns can cause pain and discomfort during dressing changes; a person's pain response varies depending on individual perception. The pain response can indicate tissue damage in the body, as pain causes a person to experience discomfort.

Immobilization of urea on beads based on OPEFB cellulose-alginate via blending to fabricate sustained release fertilizer.

Transforming oil palm empty fruit bunches (OPEFB) waste into value-added cellulose as a reinforcement agent for eco-friendly slow-release fertilizer (SRF) composites is a strategy to achieve clean and sustainable production. OPEFB cellulose was isolated by alkalization (10 % w/v NaOH) for 1 h and bleaching (30 % v/v HO) for 1.5 h.

Nephroprotective effect of sugarcane ( L.) leaves ethanol extract on gentamicin-induced nephrotoxicity in rats.

Kidney damage is commonly attributed to using certain drugs, such as gentamicin, which causes elevated kidney parameters in blood and damage to renal tissue. This damage is often a result of oxidative stress, but it can be mitigated by using antioxidants. Several studies proved the potential of sugarcane ( L.

Genetic Algorithm-based Convolutional Neural Network Feature Engineering for Optimizing Coronary Heart Disease Prediction Performance.

Objectives: This study aimed to optimize early coronary heart disease (CHD) prediction using a genetic algorithm (GA)-based convolutional neural network (CNN) feature engineering approach. We sought to overcome the limitations of traditional hyperparameter optimization techniques by leveraging a GA for superior predictive performance in CHD detection.

Methods: Utilizing a GA for hyperparameter optimization, we navigated a complex combinatorial space to identify optimal configurations for a CNN model.

Pathogenesis of Post-Tuberculosis Lung Disease: Defining Knowledge Gaps and Research Priorities at the Second International Post-Tuberculosis Symposium.

Post-tuberculosis (post-TB) lung disease is increasingly recognized as a major contributor to the global burden of chronic lung disease, with recent estimates indicating that over half of TB survivors have impaired lung function after successful completion of TB treatment. However, the pathologic mechanisms that contribute to post-TB lung disease are not well understood, thus limiting the development of therapeutic interventions to improve long-term outcomes after TB. This report summarizes the work of the Pathogenesis and Risk Factors Committee for the Second International Post-Tuberculosis Symposium, which took place in Stellenbosch, South Africa, in April 2023.

DMP-1 expression in alveolar bone socket following (Ten.) Steenis treatment: A histological study.

Objective: The study aimed to ascertain how (Ten.) Steenis Gel affects the expression of protein dentin matrix protein-1 (DMP-1) in alveolar Wistar rats after tooth extraction.

Materials And Methods: Rats were given (Ten.

A Multicenter Study of COPD and Cognitive Impairment: Unraveling the Interplay of Quantitative CT, Lung Function, HIF-1α, and Clinical Variables.

Purpose: The exact link between cognitive impairment (CI) and chronic obstructive pulmonary disease (COPD) is still limited. Thus, we aim to find the relationship and interaction of quantitative CT (QCT), lung function, HIF-1α, and clinical factors with the development of CI among COPD patients.

Patients And Methods: A cross-sectional multicentre study was conducted from January 2022 to December 2023.

Preconditioning Local Injection of Activated Platelet-Rich Plasma Increases Angiogenesis, VEGF Levels, and Viability of Modified McFarlane Flap in Diabetes-Induced Rats.

 The risk of flap necrosis in tissue reconstruction surgery is elevated in patients with vascular disorders, such as diabetes mellitus. Chronic hyperglycemia causes endothelial cell dysfunction and increases inflammatory process, causing vascular insufficiency. Platelet-rich plasma (PRP) contains high levels of platelets, growth factors, and fibrinogens.

The effect of porang () extract on renal histopathological changes.

Diabetes mellitus is a chronic condition defined by elevated blood sugar levels (hyperglycemia). This condition can lead to complications such as nephropathy, which is histologically shown with glomerulosclerosis. Glucomannan, a component of , offers numerous health benefits, but its direct therapeutic effect on glomeruli remains uncertain.

The role of Wnt signaling on Tooth Extraction Wound Healing: Narrative review.

Compared to an incisional skin or mucosal wound, a tooth extraction wound results in far more soft tissue loss. A blood clot instantly fills the gap left by the extracted tooth. An embryonic type of bone forms during the healing of extraction wounds, and mature bone only later replaces it.

Holistic Rehabilitation in Action: A Data-Driven Analysis of the Impact on Quality of Life among Individuals with Psychoactive Substance Abuse.

Psychoactive substance abuse can affect biological, psychological, social, and spiritual aspects, as well as the users' quality of life, and obliged to carry out medical and social rehabilitation. The purpose of the study was to identify the effect of holistic rehabilitation programs on quality of life among drug abusers. Quasi-experimental with time series design.

MTA as modulator of periapical tissue healing in rat molar: A histological study.

Background: Periapical surgery has been suggested as a treatment option for teeth with periapical lesions when those lesions continue despite receiving root canal therapy. Since sealing the apical region is the operation's primary goal, the choice of the root-end filling material affects how the surgery turns out. The retrofilling materials Zinc Oxide Eugenol (ZOE) and Mineral trioxide aggregate (MTA) are both known to have antibacterial characteristics.

Comprehensive studies of the anti-inflammatory effect of tetraprenyltoluquinone, a quinone from Garcinia cowa Roxb.

Ethnopharmacological Relevance: Garcinia cowa Roxb. is called asam kandis in West Sumatra. This plant contains several quinone compounds, including tetraprenyltoluquinone (TPTQ).

Determinants of Spiritual Well-Being That Impact Breast Cancer Patients' Quality of Life.

Breast cancer affects patients' quality of life, which is influenced by the body's functional abilities and the patients' spiritual well-being. Currently, there is no research on the spiritual determinants that affect quality of life in the Indonesian context. : This research analyzes the determinants of spiritual well-being in terms of breast cancer patients' quality of life using the Functional Assessment of Chronic Illness Therapy-Spiritual Well-Being (FACIT-Sp).

Prompt and aggressive treatment of deep neck infection in neglected diabetic patient: A case report and literature review.

Background: Deep neck infection (DNI) is an infection that occurs in the deep neck fascia and spaces commonly found in diabetic patients. Impaired immune system due to hyperglycemic condition in diabetic patients leads to different clinical presentations, prognosis, and management and therapy in this group of patients.

Case Presentation: We reported a deep neck infection and abscess in a diabetic patient that resulted in acute kidney injury and airway obstruction.

Association polymorphism of guanine nucleotide-binding protein β3 subunit () C825T and insertion/deletion of the angiotensin-converting enzyme () gene with peripartum cardiomyopathy.

Introduction: Peripartum cardiomyopathy (PPCM) is a potentially life-threatening pregnancy-related heart disease. Genetic roles such as gene polymorphisms may relate to the etiology of PPCM. This study analyzes the association between single nucleotide gene polymorphism (SNP) guanine nucleotide-binding protein beta-3 subunit () C825T and insertion/deletion (I/D) of the angiotensin-converting enzyme () gene with the incidence of PPCM.

Antibodies against Histoplasma capsulatum and Aspergillus fumigatus among chronic TB patients in Indonesia: a cross-sectional study.

Chronic pulmonary fungal infections may occur in patients with previous history of pulmonary tuberculosis (TB), and are often clinically misclassified as TB, especially when bacteriological confirmation for Mycobacterium tuberculosis is absent. In this study, we investigated the prevalence of antibody against Histoplasma capsulatum and Aspergillus fumigatus in patients with confirmed and clinically chronic TB. Antibodies against H.

Development of contextual learning models through collaboration between lecturers, students, and village governments in nursing education.

Purpose: This study aims to develop a contextual learning model through a collaboration between lecturers, students, and the village government for nursing education.

Methods: This study used a qualitative design. The process of collecting the data was done through focus group discussions with 12 informants representing four stakeholders.

A novel double metal-dithizone functionalized polyurethane electrospun nanofiber and film for colorimetric determination of hexavalent chromium.

This work proposes a highly specific method of Cr determination based on the double reactions of two metals, Co with dithizone to form a (DTZ)-Co complex, and the replacement of Co in the formed complex with Cr. The fast degradation of DTZ in solution in wet analysis was overcome by preparing dithizone functionalized polyurethane nanofibers that were electrospun into a membrane (DTZ/PU-NF) and a microwell plate film (DTZ/PU-MPF). For comparison, the performance of diphenylcarbazide (DPC), a currently used complexing agent for Cr, was also investigated.

immunomodulatory activity study of Roxb. fraction.

Objectives: The objective of this study is to determine the activity of Roxb. n-hexane, ethyl acetate, and butanol fractions as an immunomodulator and obtain the fraction that has the potential as an immunomodulator.

Methods: Raw 264.

The anatomical snuffbox for transradial access in arteriovenous fistula intervention: Case report and brief review of the literature.

Left distal transradial artery (dTRA) access in the anatomical snuffbox is a relatively novel technique and is considered beneficial when left TRA access is required. This technique offers essential advantages, including improved patient comfort and lower vascular complications. dTRA may provide an entry site for retrograde recanalization of the radial artery.

Microplastics in human food chains: Food becoming a threat to health safety.

While versatile application of plastics has generated huge benefits in our life, the 'plastic end-of-life' comes with downsides of emerging concern is plastic particles within all parts of environments. Plastics are highly resistant to degradation and sustain in the environment for a prolonged period resulting in easy access of microplastics into human food chain. Microplastic exposure to humans is caused by foods of both animal and plant origin, food additives, drinks, and plastic food packaging.