Diabetes and the associated complications: The role of antioxidants in diabetes therapy and care.

Diabetes mellitus (DM) is a chronic metabolic disorder characterized by high blood sugar levels (hyperglycemia). Poorly managed diabetes can lead to complications affecting multiple organ systems. Antioxidants play a crucial role in reducing oxidative stress caused by reactive oxygen species (ROS), primarily triggered by uncontrolled high blood sugar levels in diabetes.

Cellular and Molecular Activities of IP6 in Disease Prevention and Therapy.

IP6 (phytic acid) is a naturally occurring compound in plant seeds and grains. It is a poly-phosphorylated inositol derivative that has been shown to exhibit many biological activities that accrue benefits in health and diseases (cancer, diabetes, renal lithiasis, cardiovascular diseases, etc.).

Effect of leaf extract on human promyelocytic leukemia cells subjected to oxidative stress.

Objectives: has beneficial properties. However, its cytotoxicity and antioxidative effects on human promyelocytic leukemia cells (HL60) deserve investigation. Therefore, the efficacy of its crude extracts in offsetting damage in HL60 cells subjected to oxidative stress was studied.

New Frontiers for the Use of IP6 and Inositol Combination in Treating Diabetes Mellitus: A Review.

Inositol, or myo-inositol, and associated analog molecules, including myo-inositol hexakisphosphate, are known to possess beneficial biomedical properties and are now being widely studied. The impact of these compounds in improving diabetic indices is significant, especially in light of the high cost of treating diabetes mellitus and associated disorders globally. It is theorized that, within ten years, the global population of people with the disease will reach 578 million individuals, with the cost of care projected to be approximately 2.

Effects of Leaf Extract on Human Promyelocytic Leukemia Cells Subjected to Oxidative Stress.

Oxidative stress is initiated by reactive oxygen species, the primary factor in many chronic diseases. possesses strong antioxidant properties due to the presence of various phytochemicals. In this study, we investigated the effect of leaf extract on markers of oxidative stress in HL60 cells exposed to oxidative stress.