Sendai Framework sets four priority areas and 7 targets to meet in between 2015 and 2030 timeline. Of the seven Sendai Framework global targets, international attention has increasingly concentrated on the one with the most urgent deadline, target E. The target E stands for "substantially increase the number of countries with national and local disaster risk reduction strategies by 2020 The reported status of the member states is not that satisfactory in the context of meeting the deadline.
View Article and Find Full Text PDFPrevious studies reached different conclusions about whether class I hyaluronan synthases (HASs) elongate hyaluronic acid (HA) by addition to the reducing or the nonreducing end. Here we used two strategies to determine the direction of HA synthesis by purified class I HASs from Streptococcus equisimilis and Streptococcus pyogenes. In the first strategy we used each of the two UDP-sugar substrates separately to pulse label either the beginning or the end of HA chains.
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