Molecular detection of potentially zoonotic protozoa in the Chandigarh region, India.

Context: The contamination of soil by pathogenic protozoan parasites from both human and animal feces, is an important factor in the spread of parasitic infections globally. This contamination also serves as a crucial reservoir for zoonotic diseases, facilitating their transmission. In many developing nations, including India, there's limited documentation on the extent of soil contamination, which poses challenges for implementing effective One Health strategies aimed at controlling these infections.

Novel diagnostic approach for amoebic liver abscess using cell free (cf) DNA: a prospective study.

Background: Amoebic liver abscess (ALA) is commonly seen in tropical countries and diagnosis of ALA relies mainly on non-specific serological and imaging techniques as well as PCR from pus.

Objective: This study evaluated the potential of using cell free DNA (cfDNA) from serum and urine for diagnosing ALA.

Methods: We prospectively evaluated quantitative PCR (qPCR) for detection of cf DNA in serum and urine sample in all liver abscess patients.

Registered report protocol: Perceptual effects of Arabic grammatical gender on occupational expectations in a gamified speech production task.

The default use of masculine morphology to refer to all genders in Arabic-speaking countries is largely unquestioned and widely accepted. However, research on masculine generic morphology in other gender-marked languages has shown that this can create an over-representation of men and a male-bias in perception. Given the extensive use of default masculine grammatical gender in the context of job recruitment, education, and formal communication where women are typically underrepresented and men overrepresented, this widely accepted notion needs to be investigated.

Decline in IGF1 in the bone marrow microenvironment initiates hematopoietic stem cell aging.

Decline in hematopoietic stem cell (HSC) function with age underlies limited health span of our blood and immune systems. In order to preserve health into older age, it is necessary to understand the nature and timing of initiating events that cause HSC aging. By performing a cross-sectional study in mice, we discover that hallmarks of aging in HSCs and hematopoiesis begin to accumulate by middle age and that the bone marrow (BM) microenvironment at middle age induces and is indispensable for hematopoietic aging.

Mechanistic insight into carbon-carbon bond formation on cobalt under simulated Fischer-Tropsch synthesis conditions.

Facile C-C bond formation is essential to the formation of long hydrocarbon chains in Fischer-Tropsch synthesis. Various chain growth mechanisms have been proposed previously, but spectroscopic identification of surface intermediates involved in C-C bond formation is scarce. We here show that the high CO coverage typical of Fischer-Tropsch synthesis affects the reaction pathways of CH adsorbates on a Co(0001) model catalyst and promote C-C bond formation.