Synopsis of recent research by authors named "Devraj Mogare"
- Devraj Mogare's research primarily focuses on the role of the scaffold/matrix attachment region binding protein 1 (SMAR1) in cancer biology, particularly its interactions with key signaling pathways such as Wnt/β-catenin and its impact on MHC class I expression crucial for immunosurveillance.
- His findings demonstrate that down-regulation of SMAR1 is linked to cancer progression and poor prognosis, highlighting its potential as a tumor suppressor that modulates transcriptionally regulated gene expression in various malignancies, including colorectal and breast cancer.
- Additionally, Mogare explores innovative applications of chemical probes for real-time monitoring in biological systems, including the detection of hydrazine and the development of prodrugs, showcasing a multidisciplinary approach that integrates cancer biology with medicinal chemistry.
