Publications by authors named "Devon Sieving"
Article Synopsis
- Drug-induced pseudoporphyria is often caused by NSAIDs like naproxen and ibuprofen, but this case highlights meloxicam as a potential cause.
- A 55-year-old woman with multiple health issues developed skin blisters on her feet, later diagnosed as pseudoporphyria linked to her meloxicam use.
- The patient's symptoms improved after stopping meloxicam, suggesting that awareness of this medication's risk can aid dermatologists in diagnosis and treatment.
Tumor-associated macrophages (TAMs) have been shown to both aid and hinder tumor growth, with patient outcomes potentially hinging on the proportion of M1, pro-inflammatory/growth-inhibiting, to M2, growth-supporting, phenotypes. Strategies to stimulate tumor regression by promoting polarization to M1 are a novel approach that harnesses the immune system to enhance therapeutic outcomes, including chemotherapy. We recently found that nanotherapy with mesoporous particles loaded with albumin-bound paclitaxel (MSV-nab-PTX) promotes macrophage polarization towards M1 in breast cancer liver metastases (BCLM).
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