Publications by authors named "Devneet Kainth"
Article Synopsis
- Bispecific T cell engagers (BiTEs) are antibodies designed to redirect T cells towards tumors that express specific antigens, showing potential as a therapy for solid tumors like glioblastomas.
- The study focused on certain tumor-associated antigens (EGFR and IL13Rα2) found in glioma tissues and developed multivalent BiTEs to improve targeting and treatment efficacy.
- BiTE-secreting T cells showed better activation and anti-tumor responses compared to CAR T cells, particularly in early phases of treatment in a glioma mouse model, highlighting their strong therapeutic potential for solid tumors.
Cytoplasmic pressure, a function of actomyosin contractility and water flow, can regulate cellular morphology and dynamics. In mesenchymal cells, cytoplasmic pressure powers cell protrusion through physiological three-dimensional extracellular matrices. However, the role of intracellular pressure in epithelial cells is relatively unclear.
View Article and Find Full Text PDFMycobacteriophage Superphikiman is a cluster J bacteriophage which was isolated from soil collected in Philadelphia, PA. Superphikiman has a 109,799-bp genome with 239 predicted genes, including 2 tRNA genes.
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