Chemoprotective Effect of Sobatum against Lithium-Induced Oxidative Damage in Rats.

Lithium therapy mainly used in curing some psychiatric diseases responsible for numerous undesirable side effects on different organs in humans. The present study explores the beneficial effect of sobatum, a purified compound of Solanum trilobatum, on lithium carbonate (Li(2)CO(3))-induced multiple organ toxicity in rats. Li(2)CO(3) (150 mg/kg body weight) was administered orally in drinking water for a period of 30 days to induce toxicity in rats.