Publications by authors named "Devesh Radhakrishnan"
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Synopsis of recent research by authors named "Devesh Radhakrishnan"
- Devesh Radhakrishnan's research primarily focuses on optimizing monoclonal antibody (mAb) production processes, particularly through the control and enhancement of glycosylation, which is a critical quality attribute for biopharmaceutical efficacy and safety.
- His studies have utilized various methodologies to quantify and model the effects of amino acids, trace metals, and media supplementation on mAb productivity and glycosylation profiles during cell culture processes.
- Radhakrishnan has identified significant variables affecting glycan distribution in mAbs and proposed strategies for achieving desired glycan profiles consistently, thereby addressing the challenges of variability in glycosylation during biopharmaceutical production.