Hot spots localization in proteins by optimized short time Ramanujan Fourier transform.

Specific functions in biological processes are dependent on protein-protein interactions. Hot spot residues play a key role in the determination of these interactions and have wide applications in engineering proteins and drug discovery. Experimental techniques to identify hotspots are often labor intensive and expensive.

Detection of Tandem Repeats in DNA Sequences Using Short-Time Ramanujan Fourier Transform.

Tandem repeats in genomic sequences are characterized by two or more contiguous copies of a pattern of nucleotides. The role of these repeats as molecular markers is well established in various genetic disorders, human evolution studies, DNA forensics and intron retention. In this work a computational method has been developed for the extraction of both exact and approximate tandem repeats.

An adaptive window length strategy for eukaryotic CDS prediction.

Signal processing-based algorithms for identification of coding sequences (CDS) in eukaryotes are non-data driven and exploit the presence of three-base periodicity in these regions for their detection. Three-base periodicity is commonly detected using short time Fourier transform (STFT) that uses a window function of fixed length. As the length of the protein coding and noncoding regions varies widely, the identification accuracy of STFT-based algorithms is poor.