Impacting the Surface Chemistry of NiAu by Immobilizing on MgO/N-Rich Nanoporous Carbon Heterostructures for Boosting Catalytic Activities.

Tuning the physical and chemical interaction between metal-metal' (M-M') and metal-support is an ideal way to realize enhanced catalytic activity of metal nanoparticles (NPs). As a proof of concept, herein we report the fabrication of nickel-gold (Ni-Au) alloy nanoparticles attached to N-doped nanoporous carbon (NPC) intervened with MgO (NiAu@MgO-NPC), achieved through the impregnation of metal precursors into Schiff-base network polymer (SNP) framework along with Mg(OH) and pyrolysis at 800 °C in N atmosphere. With high stability and heterogeneity, the nickel rich NiAu@MgO-NPC exhibited higher catalytic activities with turnover frequencies of 29,272 h (hydrogenation of p-nitrophenol), 93,843 h (degradation of methyl orange), and 2,218 h (epoxidation of stilbene), compared to commercial 10 wt % Pd/C.

Novel thiazolinyl-picolinamide-based palladium(II) complex extenuates the virulence and biofilms of vulvovaginal candidiasis (VVC) causing Candida.

Candida infections are growing all over the world as a result of their resistance to anti-fungal drugs. This raises concerns about public health, particularly in cases of vulvovaginal candidiasis (VVC). Therefore, the need for effective treatment options for Candida infections has become crucial.

Effect of palladium(II) complexes on NorA efflux pump inhibition and resensitization of fluoroquinolone-resistant : and approach.

leads to diverse infections, and their treatment relies on the use of antibiotics. Nevertheless, the rise of antibiotic resistance poses an escalating challenge and various mechanisms contribute to antibiotic resistance, including modifications to drug targets, enzymatic deactivation of drugs, and increased efflux of antibiotics. Hence, the quest for innovative antimicrobial solutions has intensified in the face of escalating antibiotic resistance and the looming threat of superbugs.

Palladium(II) Metal Complex Fabricated Titanium Implant Mitigates Dual-Species Biofilms in Artificial Synovial Fluid.

Metallodrugs have a potent application in various medical fields. In the current study, we used a novel Palladium(II) thiazolinyl picolinamide complex that was directly fabricated over the titanium implant to examine its potency in inhibiting dual-species biofilms and exopolysaccharides. Additionally, inhibition of mono- and dual-species biofilms by coated titanium plates in an in vitro joint microcosm was performed.

Investigation on the Anticancer and Antibacterial Mechanism of Thiazoline/Imidazoline Derived Palladium(II) Complexes.

Biological activities of a series of palladium(II) complexes (M1-M9) bearing N N, N S, and N O chelating ligands are reported. The palladium complexes were tested for their cytotoxic properties against human cervical cancer (HeLa) cells and antibacterial activity against Gm and Gm bacteria. Among the palladium complexes studied (M1-M9), the complex M5, M8, and M9 were found to be more effective in inhibiting the proliferation of HeLa cells.

Transition metal complex laminated bioactive implant alleviates Methicillin Resistant Staphylococcus aureus virulence.

Orthopedic implant infections cause a serious threat after implantation. The major source of implant infection is biofilms which are highly tolerant to antibiotics due to the presence of rigid biofilm matrix. Hence to overcome biofilm mediated implant infections, we developed a novel antibiofilm agent, palladium (II) thiazolinyl picolinamide complex (Pd(II)-E).

Heteroleptic pincer palladium(II) complex coated orthopedic implants impede the AbaI/AbaR quorum sensing system and biofilm development by .

Implant-associated infections mediated by biofilms have become a major concern in the healthcare sector. As biofilm formation by this important pathogen is mediated by quorum sensing, quorum sensing inhibitors (QSI) have gained much attention. The present study confirms that novel thiazolinyl-picolinamide based palladium(II) complexes had good biofilm disruptive and QSI properties against .

Spectral Characterization of Purpurin Dye and Its Application in pH Sensing, Cell Imaging and Apoptosis Detection.

Purpurin (1,2,4-trihydroxy-9,10-anthraquinone) is a natural red dye obtained from the red madder plant that is widely used in food and dyeing industries. The present study investigated the characteristics of purpurin and its application as a pH-sensitive probe to detect the pH of solutions and intracellular pH of mammalian and bacterial cells. Purpurin exhibited high pH-sensitive behavior, low analytes interference, high stability with pKa of 4.

Quaternization and oxidation reactions of cyclodiphosphazane derivatives and their copper(I) and gold(I) complexes.

The reactions of cyclodiphosphazane derivatives cis-{(t)BuN(H)P(μ-N(t)Bu)2PN(H)(t)Bu} (1), cis-{MeN(C4H8N)P(μ-N(t)Bu)2P(NC4H8Me)} (2) and {(Me2NCH2CH2O)P(μ-N(t)Bu)2P(OCH2CH2NMe2)} (3) with methyl iodide and methyl triflate and their subsequent reactions with elemental sulfur and selenium are reported. Interestingly, the reactions of 1-3 with an excess of methyl iodide resulted in quaternising only one phosphorus atom in cis-[{(t)BuNHP(μ-N(t)Bu)2P(CH3)NH(t)Bu}](I) (4), two exocyclic nitrogen atoms and one of the phosphorus atoms in cis-{(Me2NC4H8N)P(μ-N(t)Bu)2P(CH3)(NC4H8NMe2)}](I)3 (7) and only two exocyclic nitrogen atoms in cis-[{(Me3NCH2CH2O)P(μ-N(t)Bu)2P(OCH2CH2NMe3)}](I)2 (8). The reaction of 1 with one equiv.

Two crystalline modifications of 1,1'-thiobis(2-naphthol).

The title compound, C(20)H(14)O(2)S, has been obtained in two monoclinic forms, which differ in their unit-cell dimensions, compactness of packing and conformation. Pairwise association of molecules occurs via complementary O-H..