Isolation, structural characterization, and molecular docking studies on the bioactive compound from n-Hexane extract of (L.) DC against the pancreatic cancer target Aurora 2 Kinase.

Objectives: Natural flora historically has played a substantial part in drug development since they serve as active ingredients in medications and templates for the synthesis of novel pharmaceuticals. is a conventionally utilised therapeutic flora in Indian pharmacopoeia. Therefore, the current study is intended to separate, structurally describe and analyse the anti-pancreatic cancer potential of isolated natural bio-constituents from (L.

A Systemic Review and Meta-analysis on Natural Resistance-associated Macrophage Protein 1 (3'-Untranslated Region) and Nucleotide-binding Oligomerization Domain-2 (rs8057341) Polymorphisms and Leprosy Susceptibility in Asian and Caucasian Populations.

The current meta-analysis aims to explore the potential correlation between natural resistance-associated macrophage protein 1 (NRAMP1) (3'-Untranslated region [3'-UTR]) and nucleotide-binding oligomerization domain-2 (NOD2 [rs8057341]) gene polymorphisms and their association with leprosy susceptibility in both Asian and Caucasian populations. Datas were retrieved from case control studies with NOD 2 and NRAMP 1 gene polymorphism associated with leprosy disease. Leprosy emerges as a particularly distinctive ailment among women on a global scale.

Systemic assessment of solute carrier family 11-member A1 (rs17235409) gene polymorphism and Risk in Asian and caucasian population: A comprehensive updated meta-analysis.

Background: The present meta-analysis was assessed to confirm the association between solute carrier family 11-member A1 (SLC11A1) gene (rs17235409) polymorphism with the Mycobacterium tuberculosis infection in the Asian and Caucasian populations.

Methods: A search was conducted using the databases including Google Scholar, Science Direct, Embase, and PubMed to find the case-control studies related to SLC11A1 gene polymorphism and tuberculosis (TB) infection. The MetaGenyo programme was used to perform statistical analyses of the data.

Assessment of biological risk among dentists during the COVID-19 Pandemic-A cross-sectional study.

Background: The health and life of a healthcare worker are repeatedly under threat due to the rising number of epidemics and pandemics. The COVID-19 pandemic is said to be fatal in people with a risky biological, demographic profile and working environment. This study is the first of its kind carried out on the dentist population from India, who were most affected during the COVID-19 pandemic.

Hybrid Conferences in the Post-COVID-19 Era: Time Yet for a Paradigm Shift for Medical Associations.

Unlabelled: Since the first COVID-19 lockdown in India was declared, all scientific conferences and related activities have been conducted in online formats (1). The ACS(I) [Association of Cutaneous Surgeons (India)] conducted its Annual National Conference called ACSICON-2021 for over 1150 delegates in mid-2021 in a hybrid mode. ACS(I) was one of the first organizations to embrace the hybrid conferencing strategy in the post-COVID-19 era in India.

A Novel Approach towards Early Detection of Obliteration in Lumbar Lordosis.

The millennial age group (18 to 30 years) spend at least 6 hours sitting, either in college or at their workspace. High screen time as a routine, is the major cause for numerous spinal problems. Despite the wide research carried out on postural abnormalities, there exists numerous unrequited queries with regards to lumbar lordosis estimations, due to indeterminate parameters such as age, gender, lifestyle and diet.

Recommendations for Cutaneous and Aesthetic Surgeries during COVID-19 Pandemic.

Background: Amid the coronavirus disease 2019 (COVID-19) pandemic, dermatologists must be prepared to restructure their practice of procedural dermatology and cutaneous aesthetic surgeries. The COVID-19 pandemic has presented several challenges and has ushered in several changes in practice such as teledermatology, with many physicians adopting virtual consultations and treatments. Performing procedures in the times of COVID-19 pandemic presents challenges such as risk of transmission to doctors and staff due to potential aerosolization, release of virus droplets during the procedures, and risk of virus transfer through the instruments both in the peri- and postoperative period.

Two-Stage Hybrid Gene Selection Using Mutual Information and Genetic Algorithm for Cancer Data Classification.

Cancer is a deadly disease which requires a very complex and costly treatment. Microarray data classification plays an important role in cancer treatment. An efficient gene selection technique to select the more promising genes is necessary for cancer classification.

3D nanorhombus nickel nitride as stable and cost-effective counter electrodes for dye-sensitized solar cells and supercapacitor applications.

Transition metal nitride based materials have attracted significant interest owing to their excellent properties and multiple applications in the field of electrochemical energy conversion and storage devices. Herein we synthesize 3D nanorhombus nickel nitride (NiN) thin films by adopting a reactive radio frequency magnetron sputtering process. The as-deposited 3D nano rhombus NiN thin films were utilized as cost-effective electrodes in the fabrication of supercapacitors (SCs) and dye-sensitized solar cells (DSSCs).

An Efficient Violet Amplified Spontaneous Emission (ASE) from a Conjugated Polymer (PFO-co-pX) in Solution.

The optical of conjugated polymer poly[(9,9-dioctylfluorenyl-2,7-diyl)-co-(2,5-p-xylene)] also known as [(PFO-co-pX), ADS145UV], dissolved in a few solvents, has been measured. The absorption, emission spectra, and quantum yield have been investigated by using a spectrophotometer and spectrofluorometer, respectively. The properties of Amplified Spontaneous Emission (ASE) of conjugated PFO-co-pX polymer under different conditions such as solvent type, concentration, and pumping energy have been examined by using the tripled frequency of a Nd:YAG laser as a source of pumping.

A High Power, Frequency Tunable Colloidal Quantum Dot (CdSe/ZnS) Laser.

Tunable lasers are essential for medical, engineering and basic science research studies. Most conventional solid-state lasers are capable of producing a few million laser shots, but limited to specific wavelengths, which are bulky and very expensive. Dye lasers are continuously tunable, but exhibit very poor chemical stability.

Gamma-Irradiation Effects on the Spectral and Amplified Spontaneous Emission (ASE) Properties of Conjugated Polymers in Solution.

In this paper, we investigate the effects of gamma (γ) radiation on the spectral and mplified spontaneous emission (ASE) properties of two conjugated polymers (CPs) viz., poly [2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH⁻PPV) (CPM) and poly{[2-[2',5'-(2″-ethylhexyloxy)phenyl]-1,4-phenylenevinylene]--[2-methoxy-5-(2'-ethylhexyloxy)-1,4-phenylene vinylene]} (BEHP--MEH⁻PPV) (BMP) in tetrahydrofuran (THF). Gamma irradiation strongly affected the photophysical properties of these CPs.

Laser from Optically Pumped Quantum Dot CdSe/ZnS in a Colloidal Liquid.

In this study, we had investigated the amplified spontaneous emission (ASE) characteristics of CdSe/ZnS quantum dot (QDs) in a colloidal liquid. A third harmonic of Nd:YAG laser (355 nm) was used to produce laser-induced fluorescence (LIF) at 605 nm with a spectral width of 0 nm [full width at half maximum (FWHM)]. When the pump power and focusing were carefully optimized, an ASE at 610 nm with a spectral width of Δλ = 8 nm (FWHM) could be obtained.

Hyperbaric oxygen therapy - can it be the new era in dentistry?

Hyperbaric oxygen therapy is a rapidly developing treatment modality in various fields of dentistry. It is the administration of 100% oxygen to the patient for a specified time period, to increase the oxygen tension in the tissues and also its dissolution in the blood. This review aims to briefly discuss the history, mode of action, indications, contraindications, complications and the applications of hyperbaric oxygen therapy in dentistry.

Hybrid Ant Bee Algorithm for Fuzzy Expert System Based Sample Classification.

Accuracy maximization and complexity minimization are the two main goals of a fuzzy expert system based microarray data classification. Our previous Genetic Swarm Algorithm (GSA) approach has improved the classification accuracy of the fuzzy expert system at the cost of their interpretability. The if-then rules produced by the GSA are lengthy and complex which is difficult for the physician to understand.