A framework for antecedents of social entrepreneurial intention: Empirical evidence and research agenda.

Social entrepreneurship (SE) increasingly contributes to diversity in entrepreneurship. The different approaches to SE suggest a variety of antecedents which drive individuals' intention to become social entrepreneurs. While this variety of antecedents is insightful, it also creates a need for systemisation and prioritization.

Domains of planning for future long-term care of adults with intellectual and developmental disabilities: Parent and sibling perspectives.

Background: Research shows that adults with intellectual and developmental disabilities (IDD) increasingly outlive caregivers, who often struggle to plan for the future and have little support and knowledge surrounding long-term care planning.

Methods: The study team conducted interviews with parents and siblings of adults with IDD and performed qualitative coding using a modified grounded theory to explore domains of future planning and identify barriers and facilitators.

Results: Themes from the interviews revealed seven major domains of future planning that should be considered by caregivers of adults with IDD.

Up: The rise of nitrous oxide abuse. An international survey of contemporary nitrous oxide use.

In recent years the recreational use of inhaled nitrous oxide gas (N2O) is becoming increasingly popular, yet little is known about the characteristics of its users or the effects they experience. This paper presents original research from the 2014 Global Drug Survey (GDS) (n=74,864). GDS runs the largest survey of recreational drug use in the world.

Reporting of problematic drinkers and the harm they cause: Assessing the role of alcohol use, sex, and age of those affected by a problematic drinker.

This study explores survey respondents' reports of alcohol-related harm created by another person's drinking and whether the experience of harm was influenced by the respondent's own risky drinking behavior and other relevant personal demographics (age and sex). Drawing from a cross-sectional survey of Australian adults, the study analyzes the likelihood that frequent risky drinkers, infrequent risky drinkers, nonrisky drinkers, and nondrinkers would report a problematic drinker and the different harms experienced as a result of the problematic drinker. The study also examines the type of harms experienced and the number of different harms experienced.

Beyond pre-loading: Understanding the associations between pre-, side- and back-loading drinking behavior and risky drinking.

This study examined the interaction between pre-, side- and back-loading drinking behaviors and their relationship to risky drinking, modeling to account for demographic characteristics. The study was based on an online non-probability panel survey of Victorian adults (18+) who purchased packaged liquor for off premises consumption in the previous 12months. Initially, 2545 participants entered the study, with 536 screened out, leaving a sample of 2008 respondents.

The effect of consuming Palmaria palmata-enriched bread on inflammatory markers, antioxidant status, lipid profile and thyroid function in a randomised placebo-controlled intervention trial in healthy adults.

Purpose: Palmaria palmata (P. Palmata) is reported to contain anti-inflammatory and antioxidant compounds albeit no study has investigated these effects in humans.

Methods: A randomised parallel placebo-controlled human intervention study was carried out to investigate the effect of consuming P.

Online reporting of pseudoephedrine pharmacy sales: does Australia require a mandatory system?

Objective: The objective of our research was to compare the reported pharmacy sales of pseudoephedrine-based medication in state where the electronic recording of sales is mandatory, Queensland, with a state where recording is voluntary, Victoria.

Methods: Unidentified, unit-record, pseudoephedrine-based medication transaction data (known as ProjectSTOP), for both states, were made available by GuildLink Pty Ltd, the data custodians. Data provided dated from roll-out, 8 November 2005 (Queensland) and 10 August 2007 (Victoria) to 16 October 2012 (the last entry at the time of request).

Random breath testing in Queensland and Western Australia: examination of how the random breath testing rate influences alcohol related traffic crash rates.

In this paper we explore the relationship between monthly random breath testing (RBT) rates (per 1000 licensed drivers) and alcohol-related traffic crash (ARTC) rates over time, across two Australian states: Queensland and Western Australia. We analyse the RBT, ARTC and licensed driver rates across 12 years; however, due to administrative restrictions, we model ARTC rates against RBT rates for the period July 2004 to June 2009. The Queensland data reveals that the monthly ARTC rate is almost flat over the five year period.

Heartbeat detection from a hydraulic bed sensor using a clustering approach.

Encouraged by previous performance of a hydraulic bed sensor, this work presents a new hydraulic transducer configuration which improves the system's ability to capture a heartbeat signal from four subjects with different body weight and height, gender, age and cardiac history. It also proposes a new approach for detecting the occurrence of heartbeats from ballistocardiogram (BCG) signals through the use of the k-means clustering algorithm, based on finding the location of the J-peaks. Preliminary testing showed that the new transducer arrangement was able to capture the occurrence of heartbeats for all the participants, and the clustering approach achieved correct heartbeat detection ranging from 98.

Refinement and evaluation of a hydraulic bed sensor.

Research indicates that long-term monitoring of vital signs and activity in elderly adults may provide opportunities for maintaining quality-of-life and extending independence into later years. Such a strategy requires development of a system to collect this data while imposing minimal intrusion into the lives of those being monitored. To further this goal, we have developed a hydraulic bed sensor to non-invasively monitor heartbeat and respiration during sleep.

Syringe disposal bins: the outcomes of a free trial for city traders in an inner-city municipality Australia.

Community responses toward discarded syringes have the potential to threaten the sustainability of harm reduction interventions. Many retailers in the central business district of Melbourne, Australia, have expressed concern about drug use and the associated discarded syringes. The Melbourne City Council has responded to these concerns through a variety of strategies.

Harm reduction programmes in the Asia--Pacific Region.

Introduction And Aims: This paper reports on the public health intervention of harm reduction to address drug use issues in the Asia-Pacific region.

Design And Methods: It is based on the report 'Situational analysis of illicit drug issues and responses in Asia and the Pacific', commissioned by the Australian National Council on Drugs Asia Pacific Drug Issues Committee. A comprehensive desk-based review based on published and unpublished literature and key informant data.

Prevalence of illicit drug use in Asia and the Pacific.

This paper reports on the prevalence of drug use in Asia and the Pacific. It is based on the report "Situational analysis of illicit drug issues and responses in Asia and the Pacific", commissioned by the Australian National Council on Drugs Asia Pacific Drug Issues Committee. Review of existing estimates of the prevalence of people who use illicit drugs from published and unpublished literature and information from key informants and regional institutions was undertaken for the period 1998 - 2004.

Drug production, trafficking and trade in Asia and Pacific Island countries.

We report here on illicit drug production, trafficking and transit routes found in the Asia Pacific region. The report is based on the 'Situational analysis of illicit drug issues and responses in Asia and the Pacific', commissioned by the Australian National Council on Drugs Asia Pacific Drug Issues Committee. The situational analysis was a comprehensive desk based review; data sources included published and unpublished literature and key informant reports.

Illicit drug use and responses in six Pacific Island countries.

We report here on the illicit drug situation in six Pacific nations: Fiji, Papua New Guinea, Samoa, Solomon Islands, Tonga and Vanuatu. The report is based on the 'Situational analysis of illicit drug issues and responses in Asia and the Pacific', commissioned by the Australian National Council on Drugs Asia Pacific Drug Issues Committee. The situational analysis was a comprehensive desk-based review; data sources included published and unpublished literature and information from key informants.

Learning to control collisions: the role of perceptual attunement and action boundaries.

The authors investigated the role of perceptual attunement in an emergency braking task in which participants waited until the last possible moment to slam on the brakes. Effects of the size of the approached object and initial speed on the initiation of braking were used to identify the optical variables on which participants relied at various stages of practice. In Experiments 1A and 1B, size and speed effects that were present early in practice diminished but were not eliminated as participants learned to initiate braking at a rate of optical expansion that varied with optical angle.

A prospective study of real-time panfungal PCR for the early diagnosis of invasive fungal infection in haemato-oncology patients.

A blinded prospective study was performed to determine whether screening of whole blood using a real-time, panfungal polymerase chain reaction (PCR) technique could predict the development of invasive fungal infection (IFI) in immunocompromised haemato-oncology patients. In all, 78 patients (125 treatment episodes) were screened twice weekly by real-time panfungal PCR using LightCyclertrade mark technology. IFI was documented in 19 treatment episodes (five proven, three probable and 11 possible), and in 12, PCR was sequentially positive.

A pilot study of CODOX-M/IVAC in primary refractory or relapsed high-grade non-Hodgkin's lymphoma. A Scotland and Newcastle Lymphoma Group Study.

Background And Objectives: The prognosis in patients with primary refractory or relapsed high grade non-Hodgkin's lymphoma (NHL) is very poor--the 5-year survival being generally reported at 10%.

Design And Methods: Multiple salvage regimens have been investigated and, while response rates of 50-80% have been noted in selected patients, the long-term prognosis remains poor. Following the encouraging results in high risk Burkitt's and Burkitt-like lymphoma using the CODOX-M and IVAC protocols, we performed a pilot study using a similar regimen in patients with primary refractory or relapsed high grade NHL.

Circadian variation of the acute and delayed response to alcohol: investigation of core body temperature variations in humans.

Very little research has been conducted on the interaction between alcohol and circadian rhythms, particularly using human subjects. This study focuses on humans' acute and delayed response to alcohol intoxication at different times of the day. The study, conducted over 8 weeks, was a within-subjects design with social drinkers consuming a dose of alcohol that would achieve a blood alcohol concentration (BAC) of 0.

Protein purification with vapor-phase carbon dioxide.

Gaseous CO2 was used as an antisolvent to induce the fractional precipitation of alkaline phosphatase, insulin, lysozyme, ribonuclease, trypsin, and their mixtures from dimethylsulfoxide (DMSO). Compressed CO2 was added continuously and isothermally to stationary DMSO solutions (gaseous antisolvent, GAS). Dissolution of CO2 was accompanied by a pronounced, pressure-dependent volumetric expansion of DMSO and a consequent reduction in solvent strength of DMSO towards dissolved proteins.

Leader protein of foot-and-mouth disease virus is required for cleavage of the p220 component of the cap-binding protein complex.

Suppression of host protein synthesis in cells infected by poliovirus and certain other picornaviruses involves inactivation of the cap-binding protein complex. Inactivation of this complex has been correlated with the proteolytic cleavage of p220, a component of the cap-binding protein complex. Since picornaviral RNA is not capped, it continues to be translated as the cap-binding protein complex is inactivated.