Primary Angiitis of the CNS: Differences in the Profile Between Subtypes and Outcomes From an Indian Cohort.

Background And Objectives: Primary angiitis of the CNS (PACNS) is a rare disease that has significant morbidity and mortality. Subtypes of PACNS can have different presentations that could be missed with certain diagnostic modalities, further increasing diagnostic complexity. We sought to distinguish the subtypes of PACNS and describe their outcomes in an Indian cohort.

Multi-contrast echo-planar imaging sequence (Echo-planar imaging mix) in clinical situations demanding faster MRI-brain scans.

Objectives: The excellent resolution offered by magnetic resonance imaging (MRI) has a trade-off in the form of scan duration. The purpose of the present study was to assess the clinical utility of echo-planar imaging mix (EPIMix), an echo-planar imaging-based MRI sequence for the brain with a short acquisition time.

Materials And Methods: This was a retrospective observational study of 50 patients, who could benefit from faster MRI brain scans.

High-Resolution Vessel Wall Imaging in Primary Angiitis of Central Nervous System.

Background: High-resolution vessel wall imaging (HRVWI) can aid in differentiating the various intracranial vasculopathies, but has been sparingly used in the diagnosis of primary angiitis of central nervous system (PACNS). This study is aimed to describe the vessel wall imaging characteristics of PACNS.

Materials And Methods: Patients with confirmed diagnosis of PACNS according to the Calabrese and Mallek criteria who had abnormal HRVWI were included in this retrospective descriptive study.

Rituximab for refractory primary angiitis of the central nervous system: Experience in two patients.

Primary Angiitis of the Central Nervous System (PACNS) is an aggressive disease with a high rate of relapse and mortality. Majority of patients attains clinical remission with a combination of glucocorticoids and cyclophosphamide. However, there is limited evidence on further management in patients who relapse or does not achieve clinical improvement while on first line treatment.

Persistent Falcine Sinus-The Variant Venous Structure With Anterior Interhemispheric Type And The Classic Posterior Location: Report of Two Cases.

A 14-year-old girl presented with suspected dermoid cyst of scalp underwent Neuroimaging to look for intracranial communication. Her neurological examination was essentially normal. On Magnetic Resonance Imaging(MRI), an anterior persistent falcine sinus(PFS) was noted draining into the middle portion of the superior sagittal sinus.

Shunt Site Localization of Direct Carotid-Cavernous Fistula Using 3D Rotational Angiography-Utility of Broken-Rim Sign.

Background: Direct carotid-cavernous fistulas (DCCF) develop due to breach in the integrity of the wall of the internal carotid artery, and its localization can sometimes be difficult due to rapid high flow shunts. We hypothesized that 3D rotational angiography could locate the fistula site accurately, where an interrupted rim of the carotid wall would be silhouetted against opacified vascular structures. This finding was described as a broken-rim sign, and in this study, we assessed the utility of this sign in the localization of the shunt point of DCCF.

Overreligious beliefs with neuropsychiatric manifestations in a young lady-Rule out Marchiafava-Bignami disease.

Marchiafava- Bignami disease is a rare condition characterized by demyelination of corpus callosum due to alcohol or malnutrition. Here we report a young lady who, due to her religious beliefs had stopped taking food and presented with neuropsychiatric manifestations. Neuroimaging was suggestive of Marchiafava Bignami disease and with adequate nutritional and thiamine therapy she had dramatic improvement clinically and had near complete resolution of lesions in neuroimaging.