Sensory Properties and Acceptability of Fermented Pearl Millet, a Climate-Resistant and Nutritious Grain, Among Consumers in the United States-A Pilot Study.

Millets are climate-resistant, potential alternatives to wheat that could provide environmental, food security, and health benefits (e.g., lower glycemic index).

Society for Immunotherapy of Cancer (SITC) consensus statement on essential biomarkers for immunotherapy clinical protocols.

Immunotherapy of cancer is now an essential pillar of treatment for patients with many individual tumor types. Novel immune targets and technical advances are driving a rapid exploration of new treatment strategies incorporating immune agents in cancer clinical practice. Immunotherapies perturb a complex system of interactions among genomically unstable tumor cells, diverse cells within the tumor microenvironment including the systemic adaptive and innate immune cells.

Older Adults' Experiences of Institutional Eating and Dining: A Qualitative Study on Mealtimes in Adult Day Centers.

As the global population ages, it is becoming increasingly important to create sustainable, health-promoting environments that support healthy aging. This study explores seniors' mealtime experiences in adult day centers (ADCs) in southern Israel, focusing on identifying health and well-being needs related to eating and dining behaviors through the lens of the healthy placemaking approach. Thematic analysis was used to analyze data from focus groups and interviews with ADC attendees and leaders across a multicultural sample of ADCs in southern Israel between April and November 2022.

Use of a Knowledge Translation Approach to Promote Implementation of Clinical Practice Guidelines in an Experiential Learning Course Within an Entry-Level Doctor of Physical Therapy Program: A Qualitative Study.

Introduction: Teaching health sciences students how to evaluate and implement clinical practice guidelines (CPGs) is challenging.

Review Of Literature: Physical therapist education offers experiential learning opportunities to teach students how to evaluate and implement CPGs. Knowledge translation (KT) guides the process of moving research evidence into practice.

Comparing intramuscular ketamine with peri-incisional bupivacaine with or without ketamine in dogs undergoing hemilaminectomy.

Objective: To investigate whether infiltrating bupivacaine with ketamine into the epaxial muscles improves quality and duration of analgesia perioperatively compared with bupivacaine alone or ketamine intramuscularly.

Study Design: Prospective blinded randomized clinical study.

Animals: A group of 66 dogs randomized into three groups (n = 22).

Cooking with confidence for autistic youth: outcomes from a pilot program evaluation model.

Objective: This article outlines the evaluation model for the Cooking with Confidence (CWC) program, developed using Bandura's Social Learning Theory as its conceptual framework. The evaluation aimed to: (1) Examine participant characteristics in the CWC program, (2) Assess changes in cooking knowledge, skill acquisition, self-efficacy, and confidence, and (3) Identify barriers and facilitators to participant engagement. CWC is a community-based educational program designed to help autistic young adults develop independent living skills and promote health through hands-on cooking classes.

Using harmonicity to facilitate binaural fusion.

Harmonicity is an organizing principle in the auditory system, facilitating auditory object formation. The goal of the current study is to determine if harmonicity also facilitates binaural fusion. Participants listened to pairs of two-tone harmonic complex tones that were harmonically or inharmonically related to each other.

Long-Term Performance and Safety of a Superficial HA Filler With Tri-Hyal Technology on Different Facial Zones: Forehead, Cheeks, Crow's Feet, and Upper Lips.

Background: The function of injectable hyaluronic acid-based fillers is to smooth dermal wrinkles formed during aging. The aim of this study is to evaluate the performance and safety of a dermal filler after its commercialization.

Methods: In this context, an 18-month prospective randomized single-blind study for the efficacy and safety of ART FILLER Fine Lines (AFFL) was performed on the forehead, the upper lip, the cheek folds, and the crow's feet.

Tenapanor Improves Abdominal Symptoms Irrespective of Changes in Complete Spontaneous Bowel Movement Frequency in Adults with Irritable Bowel Syndrome with Constipation.

Introduction: Tenapanor is a first-in-class, minimally absorbed intestinal sodium/hydrogen exchanger isoform 3 inhibitor approved by the US Food and Drug Administration for adults with irritable bowel syndrome with constipation (IBS-C). Pooled data from the phase 2b (NCT01923428) and phase 3 T3MPO-1 (NCT02621892) and T3MPO-2 (NCT02686138) studies examined the effects of tenapanor on abdominal symptoms independent of tenapanor's effect on complete spontaneous bowel movement (CSBM) frequency in adults with IBS-C.

Methods: This post hoc analysis was performed for patients with no CSBMs in ≥6 of the first 12 weeks of treatment (no-CSBM subgroup).

Arriba y Adelante: Looking Outward and Moving Ahead.

Judith E. Deutsch, PT, PhD, FAPTA, the 55th McMillan Lecturer, is professor and director of the Research in Virtual Environments and Rehabilitation Sciences (Rivers) Lab in the Doctoral Programs in Physical Therapy in the School of Health Professions at Rutgers University. Her current research includes the development and testing of virtual reality, serious games to improve mobility and fitness of individuals with neurologic health conditions, and knowledge translation to strengthen evidence-based practice.

Frequency and intensity of change of directions in German Bundesliga soccer.

The aim of this study was to investigate the change of direction (COD) frequencies and intensities of high-performance soccer players of the German Bundesliga independent of tactical and match context. COD data were collected from 18 German Bundesliga soccer teams (season 2016-2017; 308 fixtures) by an optical tracking system (OTS) (TRACAB). CODs were tracked using a modified algorithm and were sub-categorized by entry velocity (<3.

Serious Game-Based Balance Training with Augmented Kinesthetic Feedback Enhances Aspects of Postural Control in Poststroke Patients: A Randomized Clinical Trial.

Poststroke hemiparesis presents with motor asymmetry and decreased postural control leading to functional limitations. Serious games (SG) for balance rehabilitation of people with stroke may improve motor recovery, and the visual and auditory feedback provided by the SGs helps to explain the therapeutic benefits. However, the contribution of SG combined with kinesthetic and verbal cues during balance training has not been investigated.

Metabolomic profiles of stony coral species from the Dry Tortugas National Park display inter- and intraspecies variation.

Unlabelled: Coral reefs are experiencing unprecedented loss in coral cover due to increased incidence of disease and bleaching events. Thus, understanding mechanisms of disease susceptibility and resilience, which vary by species, is important. In this regard, untargeted metabolomics serves as an important hypothesis-building tool enabling the delineation of molecular factors underlying disease susceptibility or resilience.

Diet Quality is Positively Associated With Nature Relatedness in a U.S. Population: A Pilot Study.

Background: Sustainable dietary practices can help reduce greenhouse gas emissions and promote planetary health. The importance of investigating how to promote sustainable dietary practices is therefore crucial. Nature Relatedness measures an individual's connection to nature and can predict environmental concern and stewardship.

Concordance of Whole-Slide Imaging and Conventional Light Microscopy for Assessment of Pathologic Response Following Neoadjuvant Therapy for Lung Cancer.

Pathologic response is an endpoint in many ongoing clinical trials for neoadjuvant regimens, including immune checkpoint blockade and chemotherapy. Whole-slide scanning of glass slides generates high-resolution digital images and allows for remote review and potential measurement with image analysis tools, but concordance of pathologic response assessment on digital scans compared with that on glass slides has yet to be evaluated. Such a validation goes beyond previous concordance studies, which focused on establishing surgical pathology diagnoses, as it requires quantitative assessment of tumor, necrosis, and regression.

Immunotherapy response induces divergent tertiary lymphoid structure morphologies in hepatocellular carcinoma.

Tertiary lymphoid structures (TLS) are associated with improved response in solid tumors treated with immune checkpoint blockade, but understanding of the prognostic and predictive value of TLS and the circumstances of their resolution is incomplete. Here we show that in hepatocellular carcinoma treated with neoadjuvant immunotherapy, high intratumoral TLS density at the time of surgery is associated with pathologic response and improved relapse-free survival. In areas of tumor regression, we identify a noncanonical involuted morphology of TLS marked by dispersion of the B cell follicle, persistence of a T cell zone enriched for T cell-mature dendritic cell interactions and increased expression of T cell memory markers.

Culinary Home Empowerment for Food Waste Prevention and Minimization: Feasibility and Efficacy Protocol.

The purpose of this research is to evaluate the feasibility, acceptability, and preliminary efficacy of a household food-waste prevention and minimization intervention, titled the Culinary Home Empowerment for Food Waste Prevention and Minimization (CHEF-WPM), which consists of a culinary education video series for home cooks. The specific aims are to (1) assess the effects of the intervention at a population level across process (feasibility, usage, acceptability, satisfaction) and preliminary efficacy (motivation, opportunity, ability) metrics and (2) assess the effects of the intervention at a community level across process (feasibility, usage, acceptability, satisfaction) and preliminary efficacy (motivation, opportunity, ability, household food waste, sustainable dietary practices) metrics. The intervention includes eight modules, each containing three to five brief videos, as well as downloadable recipes and worksheets.

Intramyocardial immunomodulation with human CD16 monocytes to treat myocardial infarction in pig: a blind randomized preclinical trial.

Background: Human CD16 monocytes (hCD16 Ms) have proangiogenic properties. We assessed the feasibility, safety and efficacy of hCD16 Ms in a porcine model of myocardial infarction (MI).

Methods And Results: A total of 27 female Large White pigs underwent MI with reperfusion and cardiac magnetic resonance (CMR).

Evaluation of lingual oscillometric blood pressure measurement in anaesthetized pigs.

Objective: To evaluate the agreement between measurements of invasive blood pressure (IBP) and oscillometric blood pressure from the tongue (OBPton) using a multiparameter monitor.

Study Design: Unblinded, prospective, experimental study.

Animals: A total of 12 female Large White crossbreed pigs.

Inferring resource use from functional area presence in a small, single-flock of chickens in a mobile barn.

In poultry behavior research, the reliance on presence data to estimate actual resource usage has substantially increased with the advent of tracking technologies such as radio frequency identification (RFID) and image-based systems. Although such widely used technologies are fundamentally designed for presence tracking, many studies claim to use them to investigate actual resource usage. This study investigates whether the duration of chickens' presence near key resources accurately reflects their actual usage.