Publications by authors named "Detlev Hartz"
Arch Physiol Biochem
February 2010
Article Synopsis
- Sulphonylurea drugs have effectively treated type II diabetes for over fifty years by stimulating insulin release from pancreatic beta-cells.
- Certain sulphonylureas, particularly glimepiride, also modulate fatty acid processes in fat cells independently of insulin, suggesting potential advantages in treatment strategies.
- Research indicates that the insulin-releasing and fatty acid-metabolizing actions of these drugs depend on unique structural features, pointing towards the possibility of developing new sulphonylureas that optimize both insulin response and fatty acid management.
