Publications by authors named "Destiny Gibson"
Article Synopsis
- The study involved a case series using Yucatan miniature pigs to model spinal cord contusion injuries, comparing findings to human spinal cord injury cases.
- Researchers aimed to assess MRI measures of spinal cord damage severity and the preservation of key neural tissue, linking these to behavioral outcomes in varying levels of injury severity.
- Results showed that pigs with more severe injuries had worse locomotor and bladder function outcomes, paralleling findings in human cases, indicating that this pig model can inform understanding of spinal cord injuries and MRI evaluations.
Objectives: To explore filtered diffusion-weighted imaging (fDWI), in comparison with conventional magnetic resonance imaging (MRI) and diffusion tensor imaging (DTI), as a predictor for long-term locomotor and urodynamic (UD) outcomes in Yucatan minipig model of spinal cord injury (SCI). Additionally, electrical conductivity of neural tissue using D-waves above and below the injury was measured to assess correlations between fDWI and D-waves data.
Methods: Eleven minipigs with contusion SCI at T8-T10 level underwent MRI at 3T 4 h.
Gastrointestinal (GI) complications, including motility disorders, metabolic deficiencies, and changes in gut microbiota following spinal cord injury (SCI), are associated with poor outcomes. After SCI, the autonomic nervous system becomes unbalanced below the level of injury and can lead to severe GI dysfunction. The SmartPill™ is a non-invasive capsule that, when ingested, transmits pH, temperature, and pressure readings that can be used to assess effects in GI function post-injury.
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