Sperm Na, K-ATPase α4 and plasma membrane Ca-ATPase (PMCA) 4 regulation in asthenozoospermia.

Asthenozoospermia, which is characterized by reduced motility, is one of the etiologies of male infertility. Its biochemical and functional consequences include altered ATPase activity. This study investigated the activities of Na, K-ATPase and Ca-ATPase and the expression of Na, K-ATPase α4 and PMCA4 isoforms in human sperm of asthenozoospermic infertile men.