[Experience in treating episiotomies after labor with ice].

It is known from literature influence on cryotherapy on the tissue structures. It's application cause vessel constriction factor for decrease exudative inflammations and edema), save enzyme and immune activity at the cells levels and increases regenerative processes in tissues On the 324 young mothers we fix ice over episiotomies from 1st puerperal day for 3 days. As a control group were episiotomies on the 254 young mothers one cryoprophylaxis.

[Pregnancy in a rudimentary horn of the uterus].

The cases of pregnancy in the rudimentary horn are probably the rarest Mullerian anomalies. More often the pregnancy ends with an abortion in the first or the end of the second trimester. Extremely rarely (1% of the cases) end with a live birth.

[Delivery in women with heart diseases].

Pregnancy, child-bearing and puerperium raise different problems in front of obstetricians and gynecologist in regard to the type and gravidity of concomitant cardiac defects. During the time period of 1985-1989 the number of child-bearing women with cardiac diseases has increased about 7 times where 76.3% of them aged from 21 to 30 years.

[The treatment of pulmonary thromboembolism in puerperae with pelvic thrombophlebitis].

The possibilities of current conservative treatment were studied on parturients with pelvic thrombophlebitis and lung thromboembolism. It was established that performance of total hysterectomy or usage of vena cava filter in parturients with pelvic thrombophlebitis and lung thromboembolism should be made after careful evaluation and after trials of current conservative treatment (venous application of antibiotics from the sixth generation, metronidazol preparations and heparin).

[Immunoglobulins in the serum of puerperae].

Immunoglobulins G, A and M were determined in sera of parturients up to the sixth day after delivery. The study was carried out on 20 parturients, 17 of whom had normal pregnancy and parturition, 2 of whom underwent preterm delivery and one parturient suffered from pre-eclampsia. Immunoglobulins were determined from the first to the sixth day after delivery.

Production and application of monoclonal antibody specific for human chorionic gonadotropin.

Spleen cells from mice immunized with human chorionic gonadotropin (hCG) were fused with mouse myeloma cells and four hybridomas, secreting monoclonal antibodies, were selected for further studies. In cross-check tests against tissue extracts and peptide hormones it was established that mAb IB10 (IgG1) reacted positively against hCG only but not with other hormones. Ascites from this hybridoma was fractionated by ammonium sulphate precipitation and by FPLC to isolate the IgG fraction.

[Our experience in using nolitsin in puerperal infections (preliminary report)].

The therapeutic possibilities of the chemotherapeutic preparation Nolicine were studied. Clinical and laboratory parameters were followed in dynamics as well as microbiological examination of lochial and wounded secretion in dynamics. The results from the study showed that the applied preparation, when its usage is contemplated with the isolated bacterial flora, is suitable for treatment of some postpartal infections especially in women, who are allergic to antibiotics.

[Changes in specific and nonspecific immune reactivity in women with a complicated obstetrico-gynecologic status].

The immunologic status of some groups of women from the obstetric practice was, studied by using some routine immunologic tests. BT test and C-reactive protein were used in parturients with complicated puerperium. Pregnant women with preserved amniotic sac at tenth lunar month were investigated as well as pregnant women with declared labour activity and ruptured amniotic sac and women with normal pos-partial period and parturients with inflammatory process (complicated puerperium).

[Alpha-fetoprotein in the serum of puerperae].

Alpha-fetoprotein was determined in the sera of parturients with normal pregnancy and delivery, parturients with preterm delivery and with preeclampsia. Alpha-fetoprotein was determined by the plates of Behring Institute. The authors established that after delivery alpha-fetoprotein did not differ substantially in the separate groups.