External Validation of the SERC Trial Population: Comparison with the Multicenter French Cohort, the Swedish and SENOMIC Trial Populations for Breast Cancer Patients with Sentinel Node Micro-Metastasis.

Many trials confirmed the safety of omitting axillary dissection in the selected patients treated for early breast cancer. The external validity of these trials is questionable. Our study aimed to evaluate the accuracy of the French population representativity in the SERC trial and the differences between these two populations as well as comparing the French and the Swedish populations (the SENOMIC trial population and the Swedish National Breast Cancer Registry (NKBC) cohort) of patients with sentinel node (SN) micro-metastasis.

[Microsurgical tubal desterilization: an efficient procedure. Evaluation of a 42 cases cohort according to Guzick's biparametric method].

Objective: Tubal ligation tends to be a contraceptive method used by younger women. Regrets may then become more frequent. Although less tough today, microsurgical tubal reversal is a reliable technique and we report results taking into account exposure time and curing rate.

[Impotence with venous leakage. An extensive study of 49 cases detected by the artificial erection test].

Fourty nine men seeking advice for erectile impotence, in whom the serum flow rate necessary to maintain an artificial erection (MFR) exceeded the upper limit of the normal range proposed by most authors (75 ml/mn), underwent different investigations (including a study of their penile arteries, Nocturnal Penile Tumescence monitoring (NPT) and a papaverine test) in order to ascertain the organic basis of their impotence, and to define the diagnostic criteria for "venous incompetence". Several other types of treatments were attempted. Two thirds of the patients were found to have occlusions of their sexual arteries, and these were severe in one third of cases.

[Malignant melanoma in children and adolescents. 8 cases].

Eight cases of malignant melanoma developed during childhood have been recorded over a 35-year period. Treatment and course of the disease were extremely variable. Melanomas developed on giant pigmented naevi had a particularly somber prognosis: death occurred within 6, 7 and 3 months respectively in the 3 cases observed.

[Results of treating infections of the cervical mucosa with doxycycline polyphosphate in 53 infertile women].

Our study was carried out on 53 women who had been infertile for more than a year and who had cervical mucus infection. In 13 cases (group A) there was no other known associated factor to cause the infertility. In 26 cases (group B) there was an obvious associated factor and in a further 14 cases there was a latent associated factor.

[Apropos of the nature of vegetating pyodermatitis on chronic leg ulcers. Study of 7 cases].

The pyodermatitis proliferation around or on chronic leg ulcers derived from bone infection or of varicose origin is rare. The author, who has only seen 7 cases over the last ten years, stresses the importance of making an aetiological diagnosis which often has to be based on repeated histological examinations. Two clinically similar features have, in fact, very different natures and prognoses: one, pseudoepitheliomatous pyodermatitis (5 cases), is only a benign inflammatory reaction which is easily cured by simple curetage; the other, spiny cell epithlioma (2 cases), requires wide excision, or even amputation of the limb.

[Apropos of the Mali syndrome].

The authors report two original cases of profuse pigmentation associated with proliferative lesions of the lower limbs, in patients with venous incompetence, suggestive if the syndrome described by Mali and al. in 1963. One case was in fact of Kaposi's disease associated with severe thrombocytopenia which was the cause of death, despite the use of Chloraminophene-Cortancyl.

[Varicose eczema].

The term "varicose eczema", although made acceptable by its use, is ambiguous and misleading. It would prompt us to believe that varicose eczema is different from common dermatological eczema. There is no such difference, and it would be more correct to speak of eczema of the varicose patient.

[Bazin's hydroa vacciniforme : photobiological and metabolic study in 3 cases, and discussion on etiopathogenicity (author's transl)].

The authors described three cases of Bazin's hydroa vacciniforme. Study of the history of the disease enables present nosological conceptions to be better understood. Diagnosis of hydroa vacciniforme is essentially clinical : appearance of the rash, periodicity and spontaneous improvement after puberty are characteristic.

[Mucocutaneous angiomas in children. Must we still treat them?].

Muco-cutaneous angiomas are the most common vascular dysplasias in neonates born at term or especially prematurely. Rarely visible at birth, they appear during the first month of life, and always have a very great potential for development. Their extent is variable at onset, and their surface and volume, whatever their type, superficial, deep or mixed, both increase up to the age of 18 months and then diminish to be reabsorbed totally at the age of 3 to 4 years, leaving a zone of atrophic scarring with a cosmetic effect in proportion to the size of the lesion.

[Cutaneous lesions of malignant histiocytosis. About five cases (author's transl)].

Five cases of malignant histiocytosis are reported. They associate specific cutaneous lesions with the other much more classical symptoms of the illness; fever, weight loss, lymphadenopathy, splenomegaly, hepatomegaly. The principal clinical and histological findings observed during the course of the illness in these patients are described.