Publications by authors named "Desmettre T"

Background: Stroke treatment has significantly improved over the last decades, but the complexity of stroke cases requires specialized care through dedicated teams with specific knowledge and training. The National Institutes of Health Stroke Scale (NIHSS), widely used to assess neurological deficits and make treatment decisions, is reliable but requires specific training and certification. The traditional didactic training method, based on a video, may not adequately address certain NIHSS intricacies nor engage health care professionals (HCPs) in continuous learning, leading to suboptimal proficiency.

View Article and Find Full Text PDF

Background: Non-invasive ventilation (NIV) is a cornerstone in the management of acute chronic obstructive pulmonary disease (COPD) exacerbations with respiratory failure. While extensively studied in hospital settings, limited data exist on its use in the pre-hospital setting and clinical factors influencing its application. This study aimed to identify predictors of NIV use in the pre-hospital setting and to assess its association with patient-centered outcomes.

View Article and Find Full Text PDF

Acute dyspnea is a common symptom whose management is challenging in prehospital settings. Point-of-care ultrasound (POCUS) is increasingly accessible because of device miniaturization. To assess the contribution of POCUS in the prehospital management of patients with acute nontraumatic dyspnea, we performed a systematic review on nontrauma patients of any age managed in the prehospital setting for acute dyspnea and receiving a POCUS examination.

View Article and Find Full Text PDF

Prehospital detection and triage of stroke patients mostly rely on the use of large vessel occlusion prediction scales to decrease onsite time. These quick but simplified scores, though useful, prevent prehospital providers from detecting posterior strokes and isolated symptoms such as limb ataxia or hemianopia. In the present case, an ambulance was dispatched to a 46-year-old man known for ophthalmic migraines and high blood pressure, who presented isolated visual symptoms different from those associated with his usual migraine attacks.

View Article and Find Full Text PDF

Incidents involving ionizing radiation pose a risk of immediate and long-term clinical consequences for both victims and responders in the event of secondary contamination. Rapid identification of the problem and a coordinated response are crucial. This article summarizes the key challenges related to the emergency management of a single patient or multiple victims, addressing the importance of recognizing such a case, radioprotection measures, decontamination, and available treatments.

View Article and Find Full Text PDF
Article Synopsis
  • Acute respiratory failure is a serious condition often treated in emergency departments, where high-flow nasal oxygen (HFNO) is becoming a popular treatment option for patients experiencing it.
  • The study aims to compare the effectiveness of HFNO versus conventional oxygen therapy within the first hour of emergency treatment, hypothesizing that HFNO will lead to fewer patients needing further ventilatory support.
  • This trial involves 500 patients and is approved by ethical boards, with plans for results dissemination in peer-reviewed journals and conferences.
View Article and Find Full Text PDF

The first intraocular lenses (IOLs) used for cataract surgery transmitted both ultraviolet (UV) radiation and visible light to the retina. Colorless UV-blocking IOLs were introduced and rapidly adopted in the 1980s. Yellow-tinted blue-blocking (also known as blue-filtering) IOLs were marketed in the early 1990s.

View Article and Find Full Text PDF
Article Synopsis
  • - Research in emergency medicine critically evaluates existing practices, such as thrombolysis for minor strokes and the use of coagulation factors in severe polytrauma cases, to ensure they are effective.
  • - It introduces new technologies that enhance patient care in prehospital settings, like video-laryngoscopy and point-of-care troponin tests.
  • - This research also challenges and explores innovative practices, including double defibrillation and the use of pulmonary ultrasound for pneumonia, helping emergency physicians refine their approaches.
View Article and Find Full Text PDF

Introduction: Primary spontaneous pneumothorax (PSP) is the presence of air in the pleural space, occurring in the absence of trauma and known lung disease. Standardized expert guidelines on PSP are needed due to the variety of diagnostic methods, therapeutic strategies and medical and surgical disciplines involved in its management.

Methods: Literature review, analysis of the literature according to the GRADE (Grading of Recommendation, Assessment, Development and Evaluation) methodology; proposals for guidelines rated by experts, patients and organizers to reach a consensus.

View Article and Find Full Text PDF
Article Synopsis
  • Diagnosing acute heart failure (AHF) in elderly patients with acute dyspnea is challenging, prompting the study of various biomarkers for improved accuracy.
  • A multicenter study in France assessed the effectiveness of five biomarkers (NT-proBNP, hs-cTnI, ST2, galectin-3, CD146) in diagnosing AHF among 238 elderly patients over a four-year period.
  • While individual biomarker accuracies varied, NT-proBNP alone provided the best diagnostic accuracy (0.72), and combining the biomarkers did not significantly improve upon this.
View Article and Find Full Text PDF

Introduction: We prospectively investigated whether home treatment of pulmonary embolism (PE), is as effective and safe as the recommended early discharge management in terms of outcomes at 3 months.

Methods: We performed a post hoc analysis of prospectively and consecutively recorded data in acute PE patients from a tertiary care facility between January 2012 and November 2021. Home treatment was defined as discharge to home directly from the emergency department (ED) after <24 h stay.

View Article and Find Full Text PDF

To present clinical findings and multimodal imaging of three patients who developed bacillary layer detachments (BALADs) shortly after half-fluence, half-dose (HFHD) verteporfin photodynamic therapy (PDT). Retrospective observational case series. Three patients were treated with HFHD-PDT for (1) macular neovascularisation five years after resolved central serous chorioretinopathy (CSC), (2) persistent serous retinal detachment (SRD) from chronic CSC, and (3) neovascular age-related macular degeneration with persistent SRD despite intravitreal anti-VEGF therapy.

View Article and Find Full Text PDF

Introduction: Primary spontaneous pneumothorax (PSP) is the presence of air in the pleural space, occurring in the absence of trauma and known lung disease. Standardized expert guidelines on PSP are needed due to the variety of diagnostic methods, therapeutic strategies and medical and surgical disciplines involved in its management.

Methods: Literature review, analysis of literature according to the GRADE (Grading of Recommendation Assessment, Development and Evaluation) methodology; proposals for guidelines rated by experts, patients, and organizers to reach a consensus.

View Article and Find Full Text PDF
Article Synopsis
  • Management of first episodes of primary spontaneous pneumothorax (air in the chest cavity) is debated, with this study comparing simple aspiration and chest tube drainage as treatment methods.
  • The trial involved 402 adults aged 18-50 and measured lung expansion 24 hours post-treatment, finding a higher failure rate in the aspiration group (29%) compared to the chest tube group (18%).
  • Despite higher failure rates, the aspiration method resulted in less overall pain and fewer complications, with recurrence rates of pneumothorax being 20% for aspiration and 27% for drainage.
View Article and Find Full Text PDF

Purpose: To characterize the magnitude and consequences for interpretation of macular elevations associated with short posterior ciliary arteries (SPCA) extending to the fovea.

Methods: Retrospective study of 96 eyes of 138 patients who underwent multimodal imaging (color photographs, SD-OCT with OCT-angiography analysis, fluorescein angiography [FA] and indocyanine green angiography [ICG]) over a two-year period. The authors selected patients with a focal choroidal elevation (FCE) associated with a SPCA extending to the fovea.

View Article and Find Full Text PDF

The development of myopia is influenced by multiple environmental and genetic factors. A third component, epigenetics, may shed light on some of the relationships between environmental and genetic factors. Epigenetics is defined as the study of modulations of gene activity that can be transmitted over cell divisions without involving mutation of the DNA sequence.

View Article and Find Full Text PDF

Scanning laser ophthalmoscopes (SLOs) are used widely for reflectance, fluorescence or autofluorescence photography and less commonly for retroillumination imaging. SLOs scan a visible light or near-infrared radiation laser beam across the retina, collecting light from each retinal spot as it's illuminated. An SLO's clinical applications, image contrast and axial resolution are largely determined by an aperture overlying its photodetector.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to evaluate the cost-effectiveness of different triage strategies in emergency departments (EDs) during the first wave of COVID-19, focusing on imaging methods for patients with COVID-like symptoms.
  • The retrospective analysis of 3,712 patients in five French EDs found that systematic ultra-low-dose chest CT was more cost-effective than standard chest radiography, reducing ED stay by nearly 4 hours at a minimal added cost.
  • The findings suggest that implementing systematic ultra-low-dose chest CT could enhance patient management and efficiency in EDs during health crises like the COVID-19 pandemic.
View Article and Find Full Text PDF