Risk factor of elevated matrix metalloproteinase-3 gene expression in synovial fluid in knee osteoarthritis women.

Introduction: Metalloproteinases-3 (MMP3) are the main enzymes involved in cartilage degradation. Several genetic and non-genetic factors can increase the expression of MMP3 in patients with osteoarthritis (OA). This study aims to analyze the risk factors associated with the expression of the MMP3 gene rs679620 fluid synovial knee OA patients.

Low Maternal Vitamin D and Calcium Food Intake during Pregnancy Associated with Place of Residence: A Cross-Sectional Study in West Sumatran Women, Indonesia.

Background: There is a high prevalence of vitamin D deficiency in pregnancy worldwide, and variable availability of vitamin D-rich foods may affect the adequacy of vitamin D food intake in different regions.

Aim: We analysed the relationship between place of residence and maternal food intake of vitamin D and calcium in West Sumatra, Indonesia.

Methods: This cross-sectional study was conducted in 203 pregnant women.

Phytoestrogens and Their Health Effect.

Phytoestrogens have structures that are very similar to endogen estradiol derived from plants. Phytoestrogens sources are widespread in Asian regions including in Indonesia. Its have health benefits including reproductive health, heart health, a role in weight loss, hormone-dependent tumours, bone and skin health, and the immune system.