Publications by authors named "Desma Spyridopoulos"
Article Synopsis
- The study aimed to see if adding a medication called acetazolamide could help patients with high-grade brain tumors reduce their need for another medication, dexamethasone, which can have side effects.
- 30 patients participated, and they were split into two groups: one received acetazolamide and the other a placebo (which is just a pretend treatment). They checked to see if they could lower the dexamethasone dosage safely.
- The study ended early because not enough people joined, and it showed that acetazolamide didn’t help lower the dexamethasone dose as hoped.
Background: The goal of a clinical quality registry is to deliver immediate gains in survival and quality of life by delivering timely feedback to practitioners, thereby ensuring every patient receives the best existing treatment. We are developing an Australian Brain Cancer Registry (ABCR) to identify, describe, and measure the impact of the variation and gaps in brain cancer care from the time of diagnosis to the end of life.
Methods: To determine a set of clinical quality indicators (CQIs) for the ABCR, a database and internet search were used to identify relevant guidelines, which were then assessed for quality using the AGREE II Global Rating Scale.