Publications by authors named "Desiree Womser-Matlschweiger"
Article Synopsis
- Cycle stability is crucial for preparative chromatography, with Protein A affinity resins reportedly lasting up to 200 cycles under optimized conditions.
- Engineered alkaline-resistant Protein A resins can endure harsh cleaning cycles with 1 M NaOH, leading to fewer fouling issues and higher purification cycles.
- The study found that mass transfer increased by up to 40% due to a change in the diffusion mechanism, highlighting a narrow range of alkaline treatment conditions that can enhance dynamic binding capacity.
