Role of patient preferences in clinical practice guidelines: a multiple methods study using guidelines from oncology as a case.

Objective: Many treatment decisions are preference-sensitive and call for shared decision-making, notably when benefits are limited or uncertain, and harms impact quality of life. We explored if clinical practice guidelines (CPGs) acknowledge preference-sensitive decisions in how they motivate and phrase their recommendations.

Design: We performed a qualitative analysis of the content of CPGs and verified the results in semistructured interviews with CPG panel members.