Anti-Peri-implantitis Bacteria's Ability of Robusta Green Coffee Bean (Coffea Canephora) Ethanol Extract: An In Silico and In Vitro Study.

Objective:  This study was aimed to investigate RGCBE extract as antioxidant and anti-peri-implantitis bacteria through study and its potential as antioxidant, antibacterial, anti-inflammatory, antibone resorption, and proosteogenic through study.

Materials: AND METHODS:  Absorption, distribution, metabolism, excretion and toxicity prediction, molecular docking simulation, and visualization of chlorogenic acid (CGA) and coumaric acid (CA) as anti-inflammatory, antioxidant, and antibacterial were investigated . Inhibition zone by diffusion method, minimum inhibitory concentration (MIC), and minimum bactericidal concentration (MBC) of RGCBE extract against (Aa), (Pg), (Fn), and (Pi) were done.