BENNETT'S FRACTURE: A NARRATIVE REVIEW OF CURRENT LITERATURE.

Background: Bennett's fracture, a fracture-dislocation of the base of the first metacarpal, poses significant challenges due to the unique biomechanics of the thumb's carpometacarpal (CMC) joint. Effective management is critical to restoring thumb function and preventing long-term complications such as arthritis and instability.

Objective: This article provides a comprehensive overview of Bennett's fracture, including its mechanism of injury, diagnostic considerations, and management strategies, with a focus on conservative and surgical options.

Mammography Among Women Residing in Urban Versus Rural Utah: Breast Cancer Survival.

Background: Annual or biennial breast cancer screenings are recommended for women 40 and older. Women residing in rural areas have worse breast cancer survival rates than urban women, but no study has focused on rural versus urban residence in Utah regarding breast cancer screening and mortality.

Methods: Cases (n = 14,516) were women aged > 39 diagnosed with a first primary invasive breast cancer between 1998 and 2017 in Utah.

Empowering Physicians for Holistic Wellness in Diabetes Management through Mind-Body Medicine: Implications of the Psycho-Neuro-Immuno-Endocrine/Enteric Concept in Diabetes.

The psycho-neuro-immuno-endocrine/enteric (PNIE) axis is a fundamental concept in neuroscience, integral to the neuroendocrine system (NES). It encompasses the interactions between behavior, neurology, endocrinology, gut biology, and the immune system. These interactions regulate crucial metabolic processes like glucose, lipid, and protein metabolism, blood pressure, and various homeostatic functions, including blood pressure regulation, thermogenesis and pulmonary hypoxia detection.

Integration of Ayurvedic and Allopathic treatment in hereditary breast and ovarian cancer patient with Germline BRCA1 mutation for long term disease free survival: A case report.

Ovarian cancer patients with BRCA1 mutation have more susceptibility for secondary breast cancer. In females with BRCA1 mutation, the risk of developing breast carcinoma is 65% and of ovarian cancer is 39%, before 70 years of age. This is a case report of a 74 year old, post-menopausal woman diagnosed with metastatic retroperitoneal lymph node, high-grade papillary adenocarcinoma primary ovary stage IIIA in April 2004 at the age of 48 years.

Harnessing Digital Initiatives for Improved Health Outcomes in Diabetes Management: An Observational Patient Program.

Introduction: Patients with diabetes have easy access to a wide range of digital applications that may help with self-management and lower barriers; however, robust evidence of their effectiveness remains somewhat elusive. Zyla is a medical artificial intelligence (AI)-based personalized care management app that assists the treating physician in improving the standard of patient care by offering the patients comprehensive and individualized care. This preliminary evaluation of data collected through the Zyla app aims to understand the impact of diabetes disease outcomes among patients subscribed to this app.

Long-term disease-free survival of a patient of acute myeloid leukemia with superior vena cava syndrome grade 2 with adjunct Ayurvedic treatment: A case report.

Long-term disease-free survival (DFS) of 19 years and 8 months is achieved in an Indian male young patient with Acute Myeloid Leukemia (AML) with a grade 2 Superior Vena Cava (SVC) syndrome treated with chemotherapy and adjunct personalized Ayurvedic treatment with medicines having antipyretic (Jwaraghna), reduces inflammation and swelling (Shothaghna) and rejuvenating (Rasayana) properties and effective in anemia (Pandu) and respiratory diseases (Diseases of pranavaha srotasa) In January 2002, this patient was diagnosed with Pulmonary Kochs and Anti Koch's treatment was given for 6 months. However, due to persistent low-grade fever and supra clavicular lymph node enlargement, he was further investigated with X-Ray Chest in July 2002 revealing mediastinal lymphadenopathy with Right Costophrenic angle pleural effusion. (Grade 2 SVC syndrome).

Effect of multivalent ion doping on magnetic, electrical, and dielectric properties of nickel ferrite nanoparticles.

The nanoscale spinel structured ferrites co-doped with multi-valence ions are of great interest and proving to be promising for numerous applications. In light of this, herein we report tetravalent titanium ions (Ti) and divalent zinc ions (Zn) co-doped nickel ferrites with generic formula of NiFeTiZnO (x = 0.00 ≤ x ≤ 0.

The Burden and Prevention of Human Papillomavirus (HPV) Infections and Cervical Cancer in India: A Literature Review.

Human papillomavirus (HPV) is a widespread viral infection affecting the reproductive tract and is associated with multiple types of cancer. It is a significant global health concern, with cervical cancer being one of the most common cancers affecting women worldwide. HPV infection has been found in both married and unmarried women.

RECENT TRENDS IN THE USE OF CELL SALVAGER FOR ORTHOPAEDIC TRAUMA AND ELECTIVE SURGERIES-A NARRATIVE REVIEW.

Intraoperative blood loss management is a critical concern in orthopaedic surgeries, particularly in trauma and complex elective procedures. Traditionally, allogeneic blood transfusions have been used to manage significant blood loss, but they carry risks such as transfusion reactions, infections, and increased healthcare costs. Cell salvage, or autotransfusion, offers a safer alternative by collecting, processing, and reinfusing the patient's own blood during surgery.

Improved quality of life of a patient with refractory aggressive Natural Killer/ T-cell lymphoma (NKTCL) on adjunct Ayurvedic treatment protocol: A case report of ten-years follow-up.

In an Indian female patient diagnosed as an aggressive refractory Natural Killer/T-cell Lymphoma treated with radiotherapy followed by chemotherapy, long term overall survival (OS) of 10 years was achieved. She refused Bone Marrow Transplant (BMT) after relapse and opted 2nd line chemotherapy. After completion of conventional treatment, she started Oral Ayurvedic Medicines (OAM) which possess immunomodulatory, anti-inflammatory, and to a certain extent anti-cancer activity.

Ayurvedic perspective of dietary risk factors of colorectal cancers - A hospital-based case control study.

Background: The rising prevalence of colorectal cancer (CRC) may be attributed to various nutritional and behavioural factors, making both factors as important topics for discussion to the layman and the oncology community.

Objective: To explore additional dietary risk factors, other than those already known, according to the Ayurvedic perspective in CRC patients.

Methods: Detail dietary data was collected from 420 patients of CRC and 116 healthy volunteers registered at our institute with the help of a food frequency questionnaire.

Capturing Chemotherapy and Radiotherapy Dose Among Breast Cancer Patients With the Utah All-Payer Claims Database Compared With Gold-Standard Abstraction.

Objective: To evaluate the validity of the Utah statewide All-Payer Claims Database (APCD), we compared breast cancer-specific treatments and dosages with gold-standard abstraction of medical records.

Study Design: In this pilot study, breast cancer treatments were abstracted by a certified tumor registrar at the Utah Cancer Registry (UCR) for patients diagnosed in 2013 with breast cancer. The abstraction of medical records was the gold standard for comparison with treatments identified in the APCD.

Integrating Ayurvedic philosophy with modern technologies for drug research and development: A critical need of mechanistic insights for wider acceptability.

Ayurveda is a holistic science emphasizing healing and maintaining harmony and balance in the body. Medicines from natural resources and in pre-defined dosage forms are integral parts of successful Ayurvedic treatment in various diseases including complex ailments, such as cancer. Ayurvedic medicines are cocktails of several active phyto-compounds and/or natural resources and no isolated/purified molecules are used in the treatment.

Effects of Raupya Suvarna Sutashekhara, a herbo-mineral-metallic formulation as adjunct Oral Ayurvedic Medicine on long-term survival in patients of malignant brain tumor.

Background: The incidence of brain tumors poses a significant threat, particularly with high-grade tumors that exhibit rapid growth and can significantly impair the patient's quality of life, despite treatment modalities. Ayurveda, a natural system of medicines helps to enhance health benefits when used as a complementary therapy in combination with conventional treatment through various herbal, herbo-mineral or herbo-mineral-metallic formulations. One of such formulations, Raupya Suvarna Sutshekhara (RSS), has Raupya bhasma and Suvarna bhasma (incinerated Silver and Gold respectively) ingredients and they are described as Rasayana (immunomodulatory) and possess Medhya (enhances the brain functions and intelligence) activity.

Exploring intranasal drug delivery via nanocarriers: A promising glioblastoma therapy.

Glioblastoma is one of the most recurring types of glioma, having the highest mortality rate among all other gliomas. Traditionally, the standard course of treatment for glioblastoma involved maximum surgical resection, followed by chemotherapy and radiation therapy. Nanocarriers have recently focused on enhancing the chemotherapeutic administration to the brain to satisfy unmet therapeutic requirements for treating brain-related disorders.

Oral health-related quality of life among oropharyngeal cancer survivors.

Objectives: The incidence of oropharyngeal cancer continues to rise in the United States, yet studies on the quality of life (QoL) of oropharyngeal cancer patients are limited. The objective of this pilot study was to assess the impact of oral health on the QoL in oropharyngeal cancer survivors.

Materials And Methods: Oropharyngeal cancer survivors with a confirmed cancer diagnosis from 1996 to 2016 were sampled from the Utah Cancer Registry.

Risk of cardiovascular disease among head and neck cancer survivors: A population-based matched cohort study.

Background: In the United States, approximately 63,000 Americans develop head and neck cancer (HNC) annually. Our study aims were to investigate cardiovascular complications and risk factors for development of CVD among HNC survivors.

Methods: Utilizing the Utah Populations Database, a total of 1,901 HNC patients diagnosed and 7,796 birth year, sex, and birth state matched individuals from the general population were identified.

How do adolescents perceive body image and respond to body dissatisfaction?

Objectives: To assess adolescents' attitudes, satisfaction, and practices regarding their body image across body mass index (BMI) categories.

Methods: In this cross-sectional survey (2019-2020), we recorded anthropometry of 2,089 girls and boys between 13 and 17 years from semi-urban schools in western India. Multidimensional Body-Self Relations Questionnaire (MBSRQ) was used for multidimensional attitudinal assessment of body image and weight-related variables.

Selective Adjuvant Ayurvedic Treatment Modulates Immune Response and Oxidative Stress in a Patient with Carcinoma of the Pyriform Fossa, Undergoing Radiotherapy: A Case Study.

Introduction: Hypopharyngeal squamous cell carcinoma, stage III has poor prognosis with only 25% chance of 5 years of relative survival in such patients in spite of conventional treatment including radical surgery, radiotherapy, and concurrent chemotherapy.

Case Presentation: A chronic tobacco-betel nut chewer 62-year-old male patient had dysphagia with hoarseness of voice diagnosed with stage III, grade II malignant pyriform fossa. The patient underwent 9 cycles of neoadjuvant chemotherapy with Inj Paclitaxel 100 mg and Inj Cisplatin 40 mg.

Industrial manufacturing method and characterization of Ayurvedic marine drugs: mother pearl, cowry, coral and pearl.

Introduction: Ayurvedic marine drugs derived from mollusc shells and coral are regularly used by Ayurvedic physicians to treat several disease conditions like acid peptic disease, irritable bowel syndrome, osteoporosis, etc. However, standard operating procedures for manufacturing these drugs and their complete characterization have not been published in the Ayurvedic Formulary and Ayurvedic Pharmacopeia of India to date.

Methods: Present study describes the traditional manufacturing process and thorough characterization using classical and advanced analytical tools.

Effect of Sr substitution on the structural, dielectric and ferroelectric property of BaTiO.

We have performed a comprehensive study to explore the effect of Sr substitution on the structural and ferroelectric properties of BaTiO(BTO) with compositions BaSrTiOfor 0 ⩽⩽ 1. The room temperature structural investigation inferred that the samples with compositions> 0.30 has cubic phase instead of tetragonal as for pristine BTO.