Publications by authors named "Dermot O'reilly"

The trade-off between the costs of childcare provision and the benefits of having an increased proportion of women, particularly women with dependent children, in employment is one of the most taxing social issues for Western governments. In countries like Northern Ireland, the limited subsidised childcare provision for preschool and primary school children has been partially offset by a rise in informal childcare though this has been considerably hard to assess both in terms of magnitude and effect. Using the entire 2011 Census cohort of mothers with children aged 1 to 16 years of age, we argue that co-resident grandparents have a substantial positive impact on maternal labour force participation in Northern Ireland.

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Particulate matter suspended in the air that is comprised of microscopic particles with a diameter of 2.5μm or less (PM) is among the most impactful pollutants globally. Extensive evidence shows exposure to ambient PM is associated with a wide range of poor health outcomes.

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Background: Primary care plays a central role in most, if not all, health care systems including the care of vulnerable populations such as people who have been incarcerated. Studies linking incarceration records to health care data can improve understanding about health care access following release from prison. This review maps evidence from data-linkage studies about primary care use after prison release.

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There are growing concerns about the impact of pollution on maternal and infant health. Despite an extensive correlational literature, observational studies which adopt methods that seek to address potential biases due to unmeasured confounders draw mixed conclusions. Using a population database of births in Northern Ireland (NI) linked to localized geographic information on pollution in mothers' postcodes (zipcodes) of residence during pregnancy, we examine whether prenatal exposure to PM is associated with a comprehensive range of birth outcomes, including placental health.

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Background: Aimed to compare the prevalence, characteristics, and associated mortality risk of frailty in Northern Ireland (NI) and the Republic of Ireland (ROI).

Methods: Secondary analysis of the first wave of two nationally representative cohorts, the Northern Ireland Cohort for the Longitudinal Study of Ageing or NICOLA study (N = 8504) and the Irish Longitudinal Study on Ageing or TILDA study (N = 8504). Frailty was assessed using a harmonized accumulation deficits frailty index (FI) containing 30 items.

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Objectives: To estimate the incidence of adverse events of interest (AEIs) after receiving their first and second doses of coronavirus disease 2019 (COVID-19) vaccinations, and to report the safety profile differences between the different COVID-19 vaccines.

Design: We used a self-controlled case series design to estimate the relative incidence (RI) of AEIs reported to the Oxford-Royal College of General Practitioners national sentinel network. We compared the AEIs that occurred seven days before and after receiving the COVID-19 vaccinations to background levels between 1 October 2020 and 12 September 2021.

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Article Synopsis
  • Multimorbidity (presence of multiple health conditions) is prevalent among pregnant women, with 16.8% experiencing it and 3.6% having complex multimorbidity (four or more conditions) in a study of over 27,000 pregnancies.
  • The prevalence of multimorbidity increases with maternal age, ranging from 10.2% in younger women (15-19) to 21.4% in those aged 40-44.
  • Pregnant women with multimorbidity have higher rates of preterm birth (PTB), at 11.6%, compared to 6.7% in those without, and 15.6% in those with complex multimorbidity.*
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Introduction: There is a need to improve the implementation and provision of continuity of care between prison and community in order that people who have been in prison and have a history of low engagement with services or who are vulnerable receive appropriate and timely health care and treatment. Observational studies using record linkage have investigated continuity of care after release from prison but this type of research evidence has not been synthesised.

Objective: This paper presents a protocol designed to review record linkage studies about primary care utilisation after prison release in order to inform future research and guide service organisation and delivery towards people who are at-risk following release from prison.

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Background: Homelessness is a complex societal and public health challenge. Limited information exists about the population-level health and social care-related predictors and consequences of persons with lived experience of homelessness (PEH). Studies that focus on population subgroups or ad hoc questionnaires to gather data are of relatively limited generalisability to whole-population health surveillance and planning.

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Article Synopsis
  • This study developed a core outcome set for future research on pregnant women with multimorbidity to tackle issues of inconsistent outcome reporting across studies.
  • The development process involved a systematic literature search, focus groups, and Delphi surveys engaging diverse stakeholders, including affected women and healthcare professionals.
  • The final core outcome set identified 11 key outcomes, including maternal death, severe morbidity, and baby survival rates, which should be consistently measured in related research.
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  • A qualitative study was conducted to identify important outcomes for pregnant women with multiple long-term health conditions by involving women, their partners, and healthcare professionals in focus groups.
  • The study found 63 outcomes related to maternal health, child health, and healthcare utilization, with new outcomes discovered that haven't been previously emphasized in the literature.
  • Participants highlighted the importance of care processes, particularly the need for effective information sharing during transitions in healthcare, showing a consensus on the significance of various outcomes across different stakeholders.
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Background: Understanding and quantifying the differences in disease development in different socioeconomic groups of people across the lifespan is important for planning healthcare and preventive services. The study aimed to measure chronic disease accrual, and examine the differences in time to individual morbidities, multimorbidity, and mortality between socioeconomic groups in Wales, UK.

Methods: Population-wide electronic linked cohort study, following Welsh residents for up to 20 years (2000-2019).

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Background: Homelessness is a global burden, estimated to impact more than 100 million people worldwide. Individuals and families experiencing homelessness are more likely to have poorer physical and mental health than the general population. Administrative data is being increasingly used in homelessness research.

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Aims: Children in contact with social services are at high risk for mental ill health, but it is not known what proportion of the child population has contact with social services or how risk varies within this group compared to unexposed peers. We aim to quantify the extent and nature of contact with social services within the child population in Northern Ireland (NI) and the association with mental ill health. We also examine which social care experiences identify those most at risk.

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Background: There are public health concerns about an increased risk of mortality after release from prison. The objectives of this scoping review were to investigate, map and summarise evidence from record linkage studies about drug-related deaths among former adult prisoners.

Methods: MEDLINE, EMBASE, PsychINFO and Web of Science were searched for studies (January 2011- September 2021) using keywords/index headings.

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Article Synopsis
  • * Researchers will analyze data from UK health records spanning from 2000 to 2019, examining various health outcomes during different stages: antenatal, peripartum, postnatal, and long-term mental health.
  • * Ethical approval has been secured, and findings are set to be published in peer-reviewed journals and presented at major conferences for wider dissemination.
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  • * An analysis of almost 8 million health records found that a small percentage (4.85%) of individuals experienced AEIs within 7 days post-vaccination, with overall AEI rates decreasing compared to pre-vaccination levels for most vaccines except Spikevax, which showed a 20% increase after the first dose.
  • * The study concluded that COVID-19 vaccines are generally linked to a slight reduction in AEI incidence and recommended that sentinel networks should routinely report these events to monitor vaccine safety more effectively.
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  • The study looks at how many pregnant women are taking multiple medications, which has become more common over the last 20 years.
  • It gathered data from a big medical records database to see how often women used 2 or more medicines during pregnancy.
  • The findings show that about 25% of women used multiple medications in their first trimester, and some risk factors for this include being overweight, from certain ethnic groups, or being a smoker.
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Background: Cardiovascular disease (CVD) is a leading cause of death among women. CVD is associated with reduced quality of life, significant treatment and management costs, and lost productivity. Estimating the risk of CVD would help patients at a higher risk of CVD to initiate preventive measures to reduce risk of disease.

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  • Current UK vaccination policy targets high-risk individuals for future COVID-19 booster doses, but the specific groups that would benefit the most remain uncertain.
  • A study analyzed data from 30 million people across the UK to identify risk factors for severe COVID-19 outcomes in those who completed their primary vaccination and received a booster dose of certain vaccines.
  • The findings highlighted that from late December 2021 to February 2022, only a small percentage of vaccinated individuals experienced severe COVID-19 outcomes, indicating the effectiveness of the vaccination program, especially when considering variations in risk factors.
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