Publications by authors named "Derli Conceicao Munoz"
Influence of stimulus frequency on blockade induced by pancuronium and rocuronium: study on rats phrenic nerve-diaphragm preparation.
Angélica de Fátima de Assunção Braga Derli Conceição Munoz Franklin Sarmento da Silva Braga Daniele Ribeiro de Araujo Glória Maria Braga Potério
Acta Cir Bras
March 2009
Article Synopsis
- The study aimed to assess how two different stimulation frequencies (0.1 Hz and 1 Hz) affect the effectiveness of neuromuscular blockers pancuronium and rocuronium in rats' diaphragms.
- Researchers used a method that involved stimulating the diaphragms and measuring the decrease in response to the blockers over different time intervals (5, 15, and 30 minutes).
- Results showed that the 1 Hz frequency led to a significantly greater reduction in diaphragm response compared to 0.1 Hz for both types of neuromuscular blockers, indicating that stimulation frequency plays a crucial role in the effectiveness of these drugs.