Publications by authors named "Derk Pieter Allersma"
Pharmaceuticals (Basel)
September 2021
Article Synopsis
- Monoclonal antibodies are crucial for treating inflammatory bowel disease (IBD), but many patients experience non-responsiveness, highlighting the need for better response prediction methods.
- Fluorescent imaging using labeled antibodies may help reveal drug distribution and engagement, but effective probes are necessary for accurate assessments.
- Out of 12 drug conjugates tested, 5 showed potential for development as clinical tracers, while others were deemed unfeasible due to issues like aggregation, reduced brightness, or poor binding.
